S Shrishrimal, EA Kosmacek… - … medicine and cellular …, 2019 - Wiley Online Library
Radiation‐induced fibrosis (RIF) develops months to years after initial radiation exposure. RIF occurs when normal fibroblasts differentiate into myofibroblasts and lay down aberrant …
H Zhang, Y Hua, Z Jiang, J Yue, M Shi, X Zhen… - Clinical Cancer …, 2019 - AACR
Purpose: Our study aimed to investigate whether CAF (cancer-associated fibroblasts) were involved in long noncoding RNAs (lncRNA)-regulated radioresponse in esophageal …
L Shen, Q Wang, R Liu, Z Chen, X Zhang… - Nucleic acids …, 2018 - academic.oup.com
DNA double-strand break (DSB) repair is critical for the maintenance of genome stability. The current models of the mechanism of DSB repair are based on studies of DNA repair …
E Grossi, Y Sánchez, M Huarte - Biochimica Et Biophysica Acta (BBA) …, 2016 - Elsevier
Long noncoding RNAs (lncRNAs) are rapidly emerging as important regulators of gene expression in a wide variety of physiological and pathological cellular processes. In …
M Su, H Wang, W Wang, Y Wang… - Acta biochimica et …, 2018 - academic.oup.com
In order to maintain integrity of the genome, eukaryotic cells develop a complex DNA damage/repair response network, which can induce cell cycle arrest, apoptosis, or DNA …
JH Kim - International Journal of Molecular Sciences, 2019 - mdpi.com
DNA damage response (DDR) in eukaryotic cells is initiated in the chromatin context. DNA damage and repair depend on or have influence on the chromatin dynamics associated with …
Non-coding RNA (ncRNA) has recently emerged as a vital component of the DNA damage response (DDR), which was previously believed to be solely regulated by proteins. Many …
J Zhao, J Xu, M Wu, W Wang, M Wang, L Yang… - International Journal of …, 2023 - mdpi.com
Although DNA damage repair plays a critical role in cancer chemotherapy, the function of lncRNAs in this process remains largely unclear. In this study, in silico screening identified …
RF Ketley, M Gullerova - Essays in Biochemistry, 2020 - portlandpress.com
The mechanisms by which RNA acts in the DNA damage response (DDR), specifically in the repair of DNA double-strand breaks (DSBs), are emerging as multifaceted and complex …