Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Prostate cancer genetics: variation by race, ethnicity, and geography

TR Rebbeck - Seminars in radiation oncology, 2017 - Elsevier
Prostate cancer rates vary substantially by race, ethnicity, and geography. These disparities
can be explained by variation in access to screening and treatment, variation in exposure to …

Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer

E Castro, C Goh, D Olmos, E Saunders… - Journal of Clinical …, 2013 - ascopubs.org
Purpose To analyze the baseline clinicopathologic characteristics of prostate tumors with
germline BRCA1 and BRCA2 (BRCA1/2) mutations and the prognostic value of those …

NCCN guidelines insights: prostate cancer early detection, version 2.2016

PR Carroll, JK Parsons, G Andriole… - Journal of the National …, 2016 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer
Early Detection provide recommendations for prostate cancer screening in healthy men who …

Prostate cancer epidemiology

H Grönberg - The Lancet, 2003 - thelancet.com
Because more and more men are being diagnosed with prostate cancer worldwide,
knowledge about and prevention of this disease is important. Epidemiological studies have …

EAU guidelines on prostate cancer

A Heidenreich, G Aus, M Bolla, S Joniau, VB Matveev… - European urology, 2008 - Elsevier
OBJECTIVES: To present a summary of the 2007 version of the European Association of
Urology (EAU) guidelines on prostate cancer (PCa). METHODS: A literature review of the …

Prostate cancer in young men: an important clinical entity

CA Salinas, A Tsodikov, M Ishak-Howard… - Nature Reviews …, 2014 - nature.com
Prostate cancer is considered a disease of older men (aged> 65 years), but today over 10%
of new diagnoses in the USA occur in young men aged≤ 55 years. Early-onset prostate …

Molecular genetics of prostate cancer

C Abate-Shen, MM Shen - Genes & development, 2000 - genesdev.cshlp.org
Prostate cancer afflicts one man in nine over the age of 65 and represents the most
frequently diagnosed cancer in American men (Coffey 1993). Early detection through serum …

[HTML][HTML] DNA repair in prostate cancer: biology and clinical implications

J Mateo, G Boysen, CE Barbieri, HE Bryant, E Castro… - European urology, 2017 - Elsevier
Context For more precise, personalized care in prostate cancer (PC), a new classification
based on molecular features relevant for prognostication and treatment stratification is …

Hereditary prostate cancer: epidemiologic and clinical features

BS Carter, GS Bova, TH Beaty, GD Steinberg… - The Journal of …, 1993 - auajournals.org
Hereditary prostate cancer, a newly described variant of prostate cancer, is distinguished by
early age at onset and autosomal dominant inheritance within families. 1 We review the …