[HTML][HTML] Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

X Wu, W Hu, L Lu, Y Zhao, Y Zhou, Z Xiao… - … Pharmaceutica Sinica B, 2019 - Elsevier
Tumor cells along with a small proportion of cancer stem cells exist in a stromal
microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells …

Vitamin D and breast cancer: latest evidence and future steps

M Atoum, F Alzoughool - Breast cancer: basic and clinical …, 2017 - journals.sagepub.com
Vitamin D (the sunshine vitamin) plays a vital role in calcium homeostasis, skeletal
metabolism, and immune, cardiovascular, and reproductive systems' functions. The …

A review of cancer genetics and genomics studies in Africa

SO Rotimi, OA Rotimi, B Salhia - Frontiers in oncology, 2021 - frontiersin.org
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

[HTML][HTML] Association of ApaI and TaqI polymorphisms in VDR Gene with breast cancer

AH Matini, N Jafarian-Dehkordi… - Asian Pacific journal …, 2020 - ncbi.nlm.nih.gov
Background: Vitamin D inhibits cell proliferation via the vitamin D receptor (VDR), which may
affect breast cancer risk. This study aimed to investigate the association of ApaI and TaqI …

Potential diagnostic role of circulating MiRNAs in breast cancer: Implications on clinicopathological characters

M Swellam, M Hekmat, NM Hassan, MM Hefny… - Clinical …, 2018 - Elsevier
Background Circulating miRNAs are stable in body fluids and resembles their levels in
cancer tissue/cells. They have been expressed in many cancers among them is breast …

[HTML][HTML] Vitamin D pathway related polymorphisms and vitamin D receptor expression in breast cancer

I Francis, N AlAbdali, K Kapila, B John… - … Journal for Vitamin …, 2019 - econtent.hogrefe.com
Vitamin D deficiency is an emerging risk factor for breast cancer suggesting its role in breast
cancer pathogenesis. Recent evidence suggests vitamin D receptor (VDR) expression is a …

Clinical role of MiRNA 29a and MiRNA 335 on breast cancer management: their relevance to MMP2 protein level

E Ali Ahmed, SA Abd El-Basit… - … of physiology and …, 2022 - Taylor & Francis
Background Circulating miRNAs are novel biomarkers, authors aimed to investigate the
expression level of miR-29a and miR-335 and their relevance to CEA, CA15. 3, and matrix …

Association of SNP-SNP interactions between RANKL, OPG, CHI3L1, and VDR genes with breast cancer risk in Egyptian women

OG Shaker, MA Senousy - Clinical Breast Cancer, 2019 - Elsevier
Background Genetic susceptibility for breast cancer (BC) is still poorly understood. A
combination of multiple low-penetrant alleles of cancer-related genes and gene–gene …

Vitamin D receptor polymorphisms and associated miRNAs in the development of breast cancer in African American women

A Aloufi, J Aubee, KM Vargas, V Apprey, K Thompson… - Gene, 2024 - Elsevier
Breast cancer (BCa) is a prevalent form of cancer in women, exhibiting varying rates and
distribution across different ethnic groups. Among these groups, African American (AA) …

Genetic polymorphisms frequency of vitamin D receptor gene rs7975232 and rs731236 in Iraqi thalassemic patients and healthy controls compared to Arabian healthy …

AH Abbas, IB Hassan, MK Al-Malkey… - Meta Gene, 2020 - Elsevier
Abstract Background Vitamin D receptor (VDR) genetic polymorphisms have been stated to
be related with thalassemia, in addition to the environmental factors that enhanced the …