Towards precision medicine in non-alcoholic fatty liver disease

SM Francque - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) refers to the accumulation of lipid laden
vacuoles in hepatocytes, occurring in the context of visceral adiposity, insulin resistance and …

[HTML][HTML] Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: an individual participant-level data …

DQ Huang, N Noureddin, V Ajmera… - The Lancet …, 2023 - thelancet.com
Background Data are scarce regarding the development of hepatic decompensation in
patients with non-alcoholic fatty liver disease (NAFLD) with and without type 2 diabetes. We …

[HTML][HTML] Surveillance of the liver in type 2 diabetes: important but unfeasible?

S Qadri, H Yki-Järvinen - Diabetologia, 2024 - Springer
Fatty liver plays a pivotal role in the pathogenesis of the metabolic syndrome and type 2
diabetes. According to an updated classification, any individual with liver steatosis and one …

Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis with liver fibrosis as predictors of new-onset diabetes mellitus in people with HIV: A longitudinal …

WM Han, T Apornpong, HMS Lwin… - Clinical Infectious …, 2023 - academic.oup.com
Background We investigated the association between nonalcoholic fatty liver disease
(NAFLD) plus or minus a concurrent diagnosis of nonalcoholic steatohepatitis (NASH) and …

Effects of social determinants of health on mortality and incident liver‐related events and cardiovascular disease in steatotic liver disease

VL Chen, MW Song, D Suresh… - Alimentary …, 2023 - Wiley Online Library
Background Social determinants of health (SDOH) are becoming increasingly recognised as
mediators of human health. In the setting of metabolic dysfunction‐associated steatotic liver …

Exercise training improves serum biomarkers of liver fibroinflammation in patients with metabolic dysfunction‐associated steatohepatitis

SJ Harris, N Smith, B Hummer, IR Schreibman… - Liver …, 2024 - Wiley Online Library
Abstract Background and Aims Exercise training is recommended for all patients with
metabolic dysfunction‐associated steatotic liver disease and may reverse liver fibrosis …

[HTML][HTML] Screening for NAFLD—current knowledge and challenges

R Forlano, G Sigon, BH Mullish, M Yee, P Manousou - Metabolites, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver
function tests worldwide, with an estimated prevalence ranging between 19–46% in the …

[HTML][HTML] Hepatic fibrosis and cancer: the silent threats of metabolic syndrome

SL Friedman - Diabetes & Metabolism Journal, 2024 - ncbi.nlm.nih.gov
Metabolic dysfunction-associated steatotic (fatty) liver disease (MASLD), previously termed
non-alcoholic fatty liver disease, is a worldwide epidemic that can lead to hepatic …

[HTML][HTML] The surreptitious burden of nonalcoholic fatty liver disease in the elderly in the Asia-Pacific Region: an insight from the Global Burden of Disease Study 2019

P Danpanichkul, S Kongarin… - Journal of Clinical …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) represents a significant health threat worldwide.
The aging population and a rise in metabolic syndrome in Asia might influence the …

[HTML][HTML] EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

F Tacke, P Horn, VWS Wong, V Ratziu, E Bugianesi… - Journal of …, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-
alcoholic fatty liver disease (NAFLD), is defined as steatotic liver disease (SLD) in the …