Fungi that infect humans
Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …
Update on the diagnosis and treatment of Pneumocystis pneumonia
EM Carmona, AH Limper - Therapeutic advances in …, 2011 - journals.sagepub.com
Pneumocystis is an opportunistic fungal pathogen that causes an often-lethal pneumonia in
immunocompromised hosts. Although the organism was discovered in the early 1900s, the …
immunocompromised hosts. Although the organism was discovered in the early 1900s, the …
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Darwinian medicine and the 'hygiene'or 'old friends' hypothesis
GAW Rook - Clinical & Experimental Immunology, 2010 - academic.oup.com
The current synthesis of the 'hygiene hypothesis' suggests that the recent increase in chronic
inflammatory disorders is at least partly attributable to immunodysregulation resulting from …
inflammatory disorders is at least partly attributable to immunodysregulation resulting from …
Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa
M Tibayrenc, FJ Ayala - Proceedings of the National …, 2012 - National Acad Sciences
We propose that clonal evolution in micropathogens be defined as restrained recombination
on an evolutionary scale, with genetic exchange scarce enough to not break the prevalent …
on an evolutionary scale, with genetic exchange scarce enough to not break the prevalent …
Pneumocystis jirovecii—from a commensal to pathogen: clinical and diagnostic review
M Sokulska, M Kicia, M Wesołowska, AB Hendrich - Parasitology research, 2015 - Springer
Pneumocystis pneumonia is an opportunistic disease caused by invasion of unicellular
fungus Pneumocystis jirovecii. Initially, it was responsible for majority of morbidity and …
fungus Pneumocystis jirovecii. Initially, it was responsible for majority of morbidity and …
A molecular window into the biology and epidemiology of Pneumocystis spp
Pneumocystis, a unique atypical fungus with an elusive lifestyle, has had an important
medical history. It came to prominence as an opportunistic pathogen that not only can cause …
medical history. It came to prominence as an opportunistic pathogen that not only can cause …
Pneumocystis infection in humans: diagnosis and treatment
EJ Calderón, S Gutiérrez-Rivero… - Expert review of anti …, 2010 - Taylor & Francis
Pneumocystis jirovecii is an atypical fungus exhibiting pulmonary tropism and a highly
defined host specificity. It is generally regarded as an opportunistic microorganism causing …
defined host specificity. It is generally regarded as an opportunistic microorganism causing …
Pneumocystis jirovecii pneumonia in non-HIV-infected patients: new risks and diagnostic tools
HIV-negative populations at risk for PJP can be identified. Conventional PCR increases
diagnostic sensitivity but may detect asymptomatic colonization. Quantitative PCR …
diagnostic sensitivity but may detect asymptomatic colonization. Quantitative PCR …
Role of the pioneer transcription factor GATA2 in health and disease
The transcription factor GATA2 is involved in human diseases ranging from hematopoietic
disorders, to cancer, to infectious diseases. GATA2 is one of six GATA-family transcription …
disorders, to cancer, to infectious diseases. GATA2 is one of six GATA-family transcription …
Genomic insights into the host specific adaptation of the Pneumocystis genus
Pneumocystis jirovecii, the fungal agent of human Pneumocystis pneumonia, is closely
related to macaque Pneumocystis. Little is known about other Pneumocystis species in …
related to macaque Pneumocystis. Little is known about other Pneumocystis species in …