Cycles in epilepsy

PJ Karoly, VR Rao, NM Gregg, GA Worrell… - Nature Reviews …, 2021 - nature.com
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Enhancing precision in human neuroscience

S Nebe, M Reutter, DH Baker, J Bölte, G Domes… - Elife, 2023 - elifesciences.org
Human neuroscience has always been pushing the boundary of what is measurable. During
the last decade, concerns about statistical power and replicability–in science in general, but …

A fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain

D Ino, Y Tanaka, H Hibino, M Nishiyama - Nature Methods, 2022 - nature.com
Oxytocin (OT), a hypothalamic neuropeptide that acts as a neuromodulator in the brain,
orchestrates a variety of animal behaviors. However, the relationship between brain OT …

Seasonal light hours modulate peripheral clocks and energy metabolism in mice

L Small, LS Lundell, J Iversen, AM Ehrlich, M Dall… - Cell Metabolism, 2023 - cell.com
Except for latitudes close to the equator, seasonal variation in light hours can change
dramatically between summer and winter. Yet investigations into the interplay between …

Seasonal cues act through the circadian clock and pigment-dispersing factor to control EYES ABSENT and downstream physiological changes

S Hidalgo, M Anguiano, CA Tabuloc, JC Chiu - Current Biology, 2023 - cell.com
Organisms adapt to seasonal changes in photoperiod and temperature to survive; however,
the mechanisms by which these signals are integrated in the brain to alter seasonal biology …

Perspectives on adaptive dynamical systems

J Sawicki, R Berner, SAM Loos, M Anvari… - … Journal of Nonlinear …, 2023 - pubs.aip.org
Adaptivity is a dynamical feature that is omnipresent in nature, socio-economics, and
technology. For example, adaptive couplings appear in various real-world systems, such as …

Dynamics of thyroid diseases and thyroid‐axis gland masses

Y Korem Kohanim, T Milo, M Raz, O Karin… - Molecular Systems …, 2022 - embopress.org
Thyroid disorders are common and often require lifelong hormone replacement. Treating
thyroid disorders involves a fascinating and troublesome delay, in which it takes many …

Association between short-term air pollution exposure and perturbation in thyrotropin levels in 1.38 million Chinese women: A national longitudinal analysis, 2014 …

L Wang, H Xu, Y Yang, H Guan, X He, R Wu… - Journal of Hazardous …, 2024 - Elsevier
Prevalence of subclinical hypothyroidism substantially increased during the last decade in
China, which has been commonly/clinically diagnosed as elevation in thyrotropin (thyroid …

Association between early life adversity and allostatic load in girls with precocious puberty

J Li, Y Yu, J Yuan, D Liu, J Fang, P Wu, Y Zhou… - …, 2023 - Elsevier
Context The mechanisms underlying the elevated long-term health risk in girls with
precocious puberty remain unclear, but might result from physiological wear and tear …

Population-wide analysis of hospital laboratory tests to assess seasonal variation and temporal reference interval modification

VP Muse, A Aguayo-Orozco, SB Balaganeshan… - Patterns, 2023 - cell.com
Summary We identified mortality-, age-, and sex-associated differences in relation to
reference intervals (RIs) for laboratory tests in population-wide data from nearly 2 million …