Accelerated MR spectroscopic imaging—a review of current and emerging techniques

W Bogner, R Otazo, A Henning - NMR in Biomedicine, 2021 - Wiley Online Library
Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …

Acquisition strategies for spatially resolved magnetic resonance detection of hyperpolarized nuclei

GJ Topping, C Hundshammer, L Nagel… - … Resonance Materials in …, 2020 - Springer
Hyperpolarization is an emerging method in magnetic resonance imaging that allows
nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six …

Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients

JW Gordon, HY Chen, A Autry, I Park… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To develop and translate a metabolite‐specific imaging sequence using a
symmetric echo planar readout for clinical hyperpolarized (HP) Carbon‐13 (13C) …

Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi‐echo balanced steady‐state free precession at 3 T

CA Müller, C Hundshammer, M Braeuer… - NMR in …, 2020 - Wiley Online Library
The aim of this study was to acquire the transient MRI signal of hyperpolarized tracers and
their metabolites efficiently, for which specialized imaging sequences are required. In this …

Coil profile estimation strategies for parallel imaging with hyperpolarized 13C MRI

RB Hansen, JD Sánchez‐Heredia… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To investigate auto‐and pre‐calibration coil profile estimation for parallel imaging
reconstruction of hyperpolarized 13C MRI volumetric data. Methods Parallel imaging …

A reproducible dynamic phantom for sequence testing in hyperpolarised 13C-magnetic resonance

R Chowdhury, MV Papoutsaki, CA Müller… - The British Journal of …, 2022 - academic.oup.com
Objective To develop a phantom system which can be integrated with an automated
injection system, eliminating the experimental variability that arises with manual injection; for …

Dynamic volumetric hyperpolarized 13C imaging with multi‐echo EPI

K Deh, KL Granlund, R Eskandari, N Kim… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To generate dynamic, volumetric maps of hyperpolarized [1‐13C] pyruvate and its
metabolic products in vivo. Methods Maps of chemical species were generated with iterative …

High intrarenal lactate production inhibits the renal pseudohypoxic response to acutely induced hypoxia in diabetes

C Laustsen, K Lipsø, JA Østergaard, PM Nielsen… - Tomography, 2019 - mdpi.com
Intrarenal hypoxia develops within a few days after the onset of insulinopenic diabetes in an
experimental animal model (ie, a model of type-1 diabetes). Although diabetes-induced …

Enabling clinical Hyperpolarised 13C-MR cancer imaging through phantom development, pulse sequence optimisation and quantitative image processing

R Chowdhury - 2023 - discovery.ucl.ac.uk
Hyperpolarised 13C-Magnetic Resonance Imaging (13C-MR), via dissolution Dynamic
Nuclear Polarisation (d-DNP), is an emerging technique which uses a non-ionising contrast …

Sampling Strategies in Dynamic Hyperpolarized NMR

RE Hurd, AP Chen - Dynamic Hyperpolarized Nuclear Magnetic …, 2021 - Springer
Dynamic hyperpolarized (HP) metabolic imaging, using agents such as [1-13C] pyruvate,
requires sampling strategies that accommodate space, time, and spectral domains …