Helminths (worms) are one of the most successful organisms in nature given their ability to
infect millions of humans and animals worldwide. Their success can be attributed to their …

Sheep, goats and cattle represent the most numerous and economically important
agricultural species worldwide used as sources for milk, fibre and red meat. In addition, in …

Fasciola hepatica is a helminth pathogen that drives Th2/Treg immune responses in its
mammalian host. The parasite releases a large number of molecules that are critical to …

The spatial organization of gene expression dictates tissue functions in multicellular
parasites. Here, we present the spatial transcriptome of a parasitic flatworm, the common …

Liver flukes of animals are parasitic flatworms (Platyhelminthes: Digenea) of major
socioeconomic importance in many countries. Key representatives, such as Fasciola …

The liver fluke Fasciola hepatica is an economically important pathogen of livestock
worldwide, as well as being an important neglected zoonosis. Parasite control is reliant on …

Background Liver fluke infection of livestock causes economic losses of over US $3 billion
worldwide per annum. The disease is increasing in livestock worldwide and is a re …

We have previously reported that Trichinella spiralis glutathione-S-transferase (TsGST)
gene is an up-regulated gene in intestinal infective larvae (IIL) compared to muscle larvae …

The glutathione transferase (GST) system of parasites represents the main detoxification
mechanism of hydrophobic and electrophilic compounds. Parasites lack the CYP450 …

Purpose Galactokinase (GALK1) deficiency is a rare hereditary galactose metabolism
disorder. Beyond cataract, the phenotypic spectrum is questionable. Data from affected …