A small plant with big benefits: Fenugreek (Trigonella foenum‐graecum Linn.) for disease prevention and health promotion

KC Nagulapalli Venkata, A Swaroop… - Molecular nutrition & …, 2017 - Wiley Online Library
Plant‐derived natural products have long‐standing utility toward treating degenerative
diseases. It is estimated that about two‐thirds of world population depend on traditional …

BCAA metabolism and insulin sensitivity–Dysregulated by metabolic status?

NP Gannon, JK Schnuck… - Molecular nutrition & food …, 2018 - Wiley Online Library
Branched‐chain amino acids (BCAAs) appear to influence several synthetic and catabolic
cellular signaling cascades leading to altered phenotypes in mammals. BCAAs are most …

[HTML][HTML] Diosgenin, 4-hydroxyisoleucine, and fiber from fenugreek: mechanisms of actions and potential effects on metabolic syndrome

S Fuller, JM Stephens - Advances in Nutrition, 2015 - Elsevier
Metabolic syndrome and its complications continue to rise in prevalence and show no signs
of abating in the immediate future. Therefore, the search for effective treatments is a high …

Isolated compounds from natural products with potential antidiabetic activity-a systematic review

ACM Munhoz, TS Frode - Current diabetes reviews, 2018 - benthamdirect.com
Background: Worldwide, Type 2 diabetes has become a growing health problem. While
many research articles in the field of ethnopharmacology have focused on the antidiabetic …

Inhibitory effect of epigallocatechin-3-O-gallate on α-glucosidase and its hypoglycemic effect via targeting PI3K/AKT signaling pathway in L6 skeletal muscle cells

L Xu, W Li, Z Chen, Q Guo, C Wang… - International journal of …, 2019 - Elsevier
Abstract Epigallocatechin-3-O-gallate (EGCG), a tea polyphenol is renowned for its anti-
diabetic properties, however limited studies elucidate its hypoglycemic mechanism from …

4-Hydroxyisoleucine from Fenugreek (Trigonella foenum-graecum): Effects on Insulin Resistance Associated with Obesity

A Avalos-Soriano, R De la Cruz-Cordero, JL Rosado… - Molecules, 2016 - mdpi.com
Obesity and insulin resistance (IR) are interdependent multifactorial processes that cannot
be understood separately. Obesity leads to systemic inflammation and increased levels of …

Indian Traditional medicinal plants as a source of potent Anti-diabetic agents: A Review

VP Gaonkar, K Hullatti - Journal of diabetes & metabolic disorders, 2020 - Springer
Objective The present review aims to provide an overview of traditional medicinal plants
known to be of anti-diabetic potential. Methods A literature search was conducted using the …

Activation of IGF-1/GLP-1 signalling via 4-hydroxyisoleucine prevents motor neuron impairments in experimental ALS-rats exposed to methylmercury-induced …

A Shandilya, S Mehan, S Kumar, P Sethi, AS Narula… - Molecules, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes
progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like …

Role of Fenugreek, Cinnamon, Curcuma longa, Berberine and Momordica charantia in Type 2 Diabetes Mellitus Treatment: A Review

M Cortez-Navarrete, KG Pérez-Rubio… - Pharmaceuticals, 2023 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a complex disease that has become a major global
health concern. Given the efficacy of antidiabetic drugs, pharmacological therapy is …

[HTML][HTML] Cardioprotective effects of Fenugreek (Trigonella foenum-graceum) seed extract in streptozotocin induced diabetic rats

S Bafadam, M Mahmoudabady… - … of Cardiovascular and …, 2021 - ncbi.nlm.nih.gov
Introduction: Inadequate control of diabetes mellitus (DM) leads to considerable
cardiovascular implications like diabetic cardiomyopathy (DCM). Cardiomyocyte apoptosis …