The extent of the effect of cellular crowding and cosolutes on the functioning of proteins and
cells is manifold and includes the stabilization of the biomolecular systems, the excluded …

Decades of nuclear activities have left a legacy of hazardous radioactive waste, which must
be isolated from the biosphere for over 100,000 years. The preferred option for safe waste …

Using enzymes for the catalysis of synthetically interesting chemical reactions enables high
selectivity under mild conditions. However, for biocatalysis to be viable in an industrial …

Fungi are the most diverse living organisms on planet Earth, where their ubiquitous
presence in various ecosystems offers vast potential for the research and discovery of new …

Since its introduction in the early 1970s, high pressure crystallography (HPX) has shown
great potential for the investigation of different types of matter. Using diamond anvil cells …

Neutron spectroscopy uniquely and non-destructively accesses diffusive dynamics in soft
and biological matter, including for instance proteins in hydrated powders or in solution, and …

The mechanism of protein denaturation under pressure is still an active area of research.
Using extensive molecular dynamics simulations, for a partially unfolded structures of BPTI …

Truncated hemoglobins (TrHbs) have an ancient origin and are widely distributed in
microorganisms where they often serve roles other than dioxygen transport and storage. In …

Life as we know it from our close environment corresponds to very narrow windows in
external conditions, be it for temperature, pressure, pH, salinity or others. As they are …