Neurological deficits are a serious and common sequelae of congenital heart disease
(CHD). While their underlying mechanisms have not been fully characterized, their …

The advantages and disadvantages of using corticosteroids in children undergoing cardiac
surgery is still contentious. To examine how perioperative corticosteroids affect …

Background Acute kidney injury constitutes a major complication of cardiac surgery in
pediatric patients. The present meta-analysis aims to accumulate current literature and …

For decades, physicians have administered corticosteroids in the perioperative period to
infants undergoing heart surgery with cardiopulmonary bypass (CPB) to reduce the …

Various pathological factors accompanying any cardiac surgery can cause intraoperative
systemic inflammatory responses (SIR). As the number of cardiac surgical interventions …

Background Cortisol is the main stress hormone mobilised during surgery to establish
homeostasis. Our current understanding of the hypothalamic-pituitary-adrenal axis …

The hypothalamic-pituitary-adrenal axis is the primary neuroendocrine system activated to
re-establish homeostasis during periods of stress, including critical illness and major …

Большое количество патогенных факторов, сопровождающих любую
кардиохирургическую операцию, приводит к возникновению системного …

Background Neurodevelopmental impairment is an important consequence for survivors of
surgery for critical congenital heart disease. This study sought to determine whether …

Corticosteroids have been used to decrease the inflammatory response to cardiac surgery
and cardiopulmonary bypass in children for decades. Sparse information is present …