The clinical manifestations of COVID-19 are widely variable and may involve several
districts. Although the clinical course is mostly characterized by respiratory involvement, up …

Myocardial calcium (Ca 2+) signaling plays a crucial role in contractile function and
membrane electrophysiology. An abnormal myocardial Ca 2+ transient is linked to heart …

Class IC antiarrhythmic drugs (AADs) currently represent a cornerstone in the therapy of
atrial fibrillation, both for the restoration of sinus rhythm and for the prophylaxis of long-term …

Arrhythmogenic cardiomyopathy (ACM) is a genetic disorder that may lead patients to
sudden cell death through the occurrence of ventricular arrhythmias. ACM is characterised …

Four days following discharge, the patient's mother recognized that the provided flecainide
had a concentration (20 mg/mL) twice of that intended (10 mg/mL). The patient had received …

Background Due to suspected pro-arrhythmic effects and increased mortality associated
with class-IC antiarrhythmic drugs (AADs) in previous trials, AAD therapy in structural heart …

Amitriptyline intoxication is caused by its suicidal or accidental overdose. In the present
study, by intravenously injecting 1.5 or 3.0 mg/kg amitriptyline into bullfrogs, we actually …

Abstract Background Brugada syndrome (BrS) is a genetic disease characterized by coved
ST-segment elevation in the right precordial leads that predispose to life-threatening …

The repercussions of coronavirus disease 2019 (COVID-19) have been devastating on a
global scale. Long COVID, which affects patients for weeks or even months after their initial …

Cardiac arrhythmias occur in 6% to 17% of COVID-19 patients. Their prevalence is
significantly higher (up to 44%) in patients admitted to intensive care unit, becoming the …