Differential Effects of Mutations of Popeye Domain Containing Proteins on Heteromeric Interaction and Membrane Trafficking
AH Swan, RFR Schindler, M Savarese, I Mayer… - bioRxiv, 2022 - biorxiv.org
Abstract Background The Popeye domain containing (POPDC) genes encode sarcolemma-
localised cAMP effector proteins. Mutations in BVES (POPDC1) and POPDC2 have been …
localised cAMP effector proteins. Mutations in BVES (POPDC1) and POPDC2 have been …
Adenylyl cyclase 9 is auto-stimulated by its isoform-specific carboxyl terminal domain and equipped with paradigm-switching mechanisms
Z Chen, FA Antoni - bioRxiv, 2022 - biorxiv.org
Abstract Transmembrane adenylyl cyclase 9 (AC9) is unusual in not being regulated by
heterotrimeric G proteins. The key to resistance to stimulation by Gs-coupled receptors …
heterotrimeric G proteins. The key to resistance to stimulation by Gs-coupled receptors …