Visible-Light-Promoted Enantioselective Acylation and Alkylation of Aldimines Enabled by 9-Fluorenone Electron-Shuttle Catalysis

Z Zhong, H Wu, X Chen, Y Luo, L Yang… - Journal of the …, 2024 - ACS Publications
Chiral acyclic α-tertiary amino ketones are widely present in various natural products and
pharmaceuticals; however, the direct synthesis of this pharmacophore through a robust …

Catalytic Enantioselective Aldol Reactions of Pyruvates as Nucleophiles with Chlorinated and Fluorinated Aldehydes and Ketones

S Mondal, F Tanaka - The Journal of Organic Chemistry, 2024 - ACS Publications
Reactions of pyruvates as nucleophiles under catalytic conditions are difficult to control
without the use of enzymes as catalysts. Here, enantioselective aldol reactions of pyruvates …

Organocatalytic enantioselective Mannich and retro-Mannich reactions and combinations of these reactions to afford tetrasubstituted α-amino acid derivatives

KL Chen, F Tanaka - Organic & Biomolecular Chemistry, 2024 - pubs.rsc.org
Organocatalytic asymmetric Mannich reactions and kinetic resolutions of the products via
retro-Mannich reactions that afford enantiomerically enriched tetrasubstituted α-amino acid …