Exosomes: key players in cancer and potential therapeutic strategy
J Dai, Y Su, S Zhong, L Cong, B Liu, J Yang… - Signal transduction and …, 2020 - nature.com
Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …
Biological roles and mechanisms of circular RNA in human cancers
Q Tang, SS Hann - OncoTargets and therapy, 2020 - Taylor & Francis
Circular RNA (circRNA) is an intriguing class of RNA with covalently closed-loop structure
and is highly stable and conservative. As new members of the ncRNAs, the function …
and is highly stable and conservative. As new members of the ncRNAs, the function …
Identification of circRNA-lncRNA-miRNA-mRNA competitive endogenous RNA network as novel prognostic markers for acute myeloid leukemia
Y Cheng, Y Su, S Wang, Y Liu, L Jin, Q Wan, Y Liu, C Li… - Genes, 2020 - mdpi.com
Background: Acute myeloid leukemia (AML) is one of the most common malignant and
aggressive hematologic tumors, and its pathogenesis is associated with abnormal post …
aggressive hematologic tumors, and its pathogenesis is associated with abnormal post …
Emerging functions of circular RNA in aging
Circular RNA (circRNA) is a closed, single-stranded transcript widely detected in eukaryotes.
Recent studies indicate that the levels of circRNAs change with age in various tissues in …
Recent studies indicate that the levels of circRNAs change with age in various tissues in …
Impact of exosome therapy on pancreatic cancer and its progression
Pancreatic cancer, one of the most aggressive tumors, has a dismal prognosis because of
the low rates of early identification, fast progression, difficulties following surgery, and the …
the low rates of early identification, fast progression, difficulties following surgery, and the …
The long and short of it: the emerging roles of non-coding RNA in small extracellular vesicles
A Abramowicz, MD Story - Cancers, 2020 - mdpi.com
Small extracellular vesicles (EVs) play a significant role in intercellular communication
through their non-coding RNA (ncRNA) cargo. While the initial examination of EV cargo …
through their non-coding RNA (ncRNA) cargo. While the initial examination of EV cargo …
Circ_0009910 shuttled by exosomes regulates proliferation, cell cycle and apoptosis of acute myeloid leukemia cells by regulating miR‐5195‐3p/GRB10 axis
D Wang, X Ming, J Xu, Y Xiao - Hematological oncology, 2021 - Wiley Online Library
The exosomes are involved in intercellular communication via RNA trafficking in human
diseases. Hsa_circ_0009910 (circ_0009910) is a novel leukemia‐related circular RNA …
diseases. Hsa_circ_0009910 (circ_0009910) is a novel leukemia‐related circular RNA …
Protein-related circular RNAs in human pathologies
O Wawrzyniak, Ż Zarębska, K Kuczyński… - Cells, 2020 - mdpi.com
Circular RNAs (circRNAs) are a distinct family of RNAs derived from alternative splicing
which play a crucial role in regulating gene expression by acting as microRNA (miRNA) and …
which play a crucial role in regulating gene expression by acting as microRNA (miRNA) and …
Circular RNAs in blood malignancies
O Perez de Acha, M Rossi, M Gorospe - Frontiers in molecular …, 2020 - frontiersin.org
Circular (circ) RNAs influence a wide range of biological processes at least in part by
interacting with proteins and microRNAs. CircRNAs expressed in the hematopoietic …
interacting with proteins and microRNAs. CircRNAs expressed in the hematopoietic …
Cancer-associated circRNA–miRNA–mRNA Regulatory networks: a meta-analysis
Recent advances in sequencing technologies and the discovery of non-coding RNAs
(ncRNAs) have provided new insights in the molecular pathogenesis of cancers. Several …
(ncRNAs) have provided new insights in the molecular pathogenesis of cancers. Several …