BACKGROUND Human pregnancy requires robust hemostasis to prevent hemorrhage
during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification …

Pregnancy success is determined by a complex progress that includes trophoblast invasion
and placentation. Matrix metalloproteinases (MMPs) and tissue inhibitors of …

In normal human placentation, uterine invasion by trophoblast cells and subsequent spiral
artery remodeling depend on cooperation among fetal trophoblasts and maternal decidual …

Preeclampsia is a multi‐system hypertensive disorder of pregnancy, with significant rates of
maternal and neonatal morbidity. It represents a major cause of preterm birth, as definitive …

Preeclampsia (PE) is a pregnancy-specific disorder characterized by hypertension and
proteinuria after 20 wk gestation. Abnormal extravillous trophoblast (EVT) invasion and …

Among several interleukin (IL)-6 family members, only IL-6 and IL-11 require a gp130
protein homodimer for intracellular signaling due to lack of intracellular signaling domain in …

Detrimental effects of maternal smoking on the term placental proteome and steroid-
metabolizing activities, and maternal hormone levels, were studied by using seven non …

Introduction Preeclampsia is a life-threatening disorder of pregnancy unique to humans.
Interleukin (IL) 11 is elevated in serum from pregnancies that subsequently develop early …

Pyroptosis is a form of programmed cell death that is crucial in the development of various
diseases, including autoimmune diseases, atherosclerotic diseases, cancer, and pregnancy …

BACKGROUND Human trophoblast invasion and differentiation are essential for a
successful pregnancy outcome. Dysregulation of these processes can lead to placental …