Characterizing the genetic structure of large cohorts has become increasingly important as genetic studies extend to massive, increasingly diverse biobanks. Popular methods …
Adversarial attacks can drastically change the output of a method by small alterations to its input. While this can be a useful framework to analyze worst-case robustness, it can also be …
Motivation: Modern biobanks provide numerous high-resolution genomic sequences of diverse populations. These datasets enable a better understanding of genotype-phenotype …
Precision medicine models often perform better for populations of European ancestry due to the over-representation of this group in the genomic datasets and large-scale biobanks from …
A fundamental goal in population genetics is to understand how variation is arrayed over natural landscapes. From first principles we know that common features such as …
M Barrabés, D Bonet, VN Moriano… - 2023 IEEE …, 2023 - ieeexplore.ieee.org
Large-scale and increasingly diverse datasets power modern genomic studies, yet robust data integration and homogenization across varying sources remains a challenge. The …
Y Wei, D Zhi, S Zhang - bioRxiv, 2023 - ncbi.nlm.nih.gov
The availability of large genotyped cohorts brings new opportunities for revealing high- resolution genetic structure of admixed populations, via local ancestry inference (LAI), the …
Admixture is a common phenomenon in human populations, resulting from the mating of individuals from two or more previously isolated populations. This can lead to the formation …
The exponential growth of genomic data demands progress and research on scalable bioinformatics algorithms. A paradigm to improve computational efficiency in bioinformatics …