Revealing fine-scale cellular heterogeneity among spatial context and the functional and
structural foundations of tissue architecture is fundamental within biological research and …

Single-cell RNA sequencing (scRNA-seq) technology is a powerful, rapidly developing tool
for characterizing individual cells and elucidating biological mechanisms at the cellular …

Pathophysiological roles of cardiac dopamine system remain unknown. Here, we show the
role of dopamine D1 receptor (D1R)-expressing cardiomyocytes (CMs) in triggering heart …

The underlying mechanisms of ventricular remodeling after myocardial infarction (MI) remain
largely unknown. In this study, we performed an integrative analysis of spatial …

Implementing Single-cell RNA sequencing (scRNA-seq) has significantly enhanced our
comprehension of cardiovascular diseases (CVDs), providing new opportunities to …

Cardiovascular disease encompasses a wide range of conditions, resulting in the highest
number of deaths worldwide. The underlying pathologies surrounding cardiovascular …

Current transcriptomics technologies, including bulk RNA-seq, single-cell RNA sequencing
(scRNA-seq), single-nucleus RNA-sequencing (snRNA-seq), and spatial transcriptomics …

Cells are minimal functional units in biological phenomena, and therefore single-cell
analysis is needed to understand the molecular behavior leading to cellular function in …

Recent advances in technology such as the introduction of high throughput
multidimensional tools like single cell sequencing help to characterize the cellular …

Eukaryotes must balance the metabolic and cell death actions of mitochondria via control of
gene expression and cell fate by chromatin, thereby functionally binding the metabolome …