Initially discovered by genetic screens in budding yeast, SPT5 and its partner SPT4 form a
stable complex known as DSIF in metazoa, which plays pleiotropic roles in multiple steps of …

Precursor messenger RNA (pre-mRNA) is processed into its functional form during RNA
polymerase II (Pol II) transcription. Although functional coupling between transcription and …

During heart development, a well-characterized network of transcription factors initiates
cardiac gene expression and defines the precise timing and location of cardiac progenitor …

Heterochromatin is a condensed chromatin structure that represses transcription of repetitive
DNA elements and developmental genes, and is required for genome stability …

RNA polymerase II transcription elongation directs an intricate pattern of histone
modifications. This pattern includes a regulatory cascade initiated by the elongation factor …

The PAF1 complex component Rtf1 is an RNA Polymerase II-interacting transcription
regulatory protein that promotes transcription elongation and the co-transcriptional …

Black gram (Vigna mungo (L.) Hepper) is a pulses crop with good digestible protein and a
high carbohydrate content, so it is widely consumed as human food and animal feed …

Abstract RNA polymerase II (RNAPII) transcription elongation directs an intricate pattern of
histone modifications. Formation of this pattern involves a highly conserved regulatory axis …

Proper regulation of gene expression is critical for organismal development and survival.
Promoter-proximal pausing of RNA Polymerase II (RNAPII) and regulated release into …

Abstract RNA polymerase II (RNAPII) transcription is coupled to co-transcriptional processes
that regulate numerous aspects of genomic function, including histone post-translational …