Bile acids as metabolic regulators and nutrient sensors

JYL Chiang, JM Ferrell - Annual review of nutrition, 2019 - annualreviews.org
Bile acids facilitate nutrient absorption and are endogenous ligands for nuclear receptors
that regulate lipid and energy metabolism. The brain–gut–liver axis plays an essential role in …

Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic disease

JC Chang - Thrombosis journal, 2019 - Springer
In addition to protective “immune response”, sepsis is characterized by destructive
“endothelial response” of the host, leading to endotheliopathy and its molecular dysfunction …

Hepatic encephalopathy 2018: A clinical practice guideline by the Italian Association for the Study of the Liver (AISF)

S Montagnese, FP Russo, P Amodio, P Burra… - Digestive and Liver …, 2019 - Elsevier
Hepatic encephalopathy (HE) is a common, worrisome and sometimes difficult to manage
complication of end-stage liver disease. HE is often recurrent, requiring multiple hospital …

Shunt-induced hepatic encephalopathy in TIPS: current approaches and clinical challenges

P Schindler, H Heinzow, J Trebicka… - Journal of Clinical …, 2020 - mdpi.com
Transjugular intrahepatic portosystemic shunt (TIPS) is an established treatment tool in
decompensated liver cirrhosis that has been shown to prolong transplant-free survival …

[HTML][HTML] Ammonia exposure induced intestinal inflammation injury mediated by intestinal microbiota in broiler chickens via TLR4/TNF-α signaling pathway

Y Zhou, M Zhang, X Zhao, J Feng - Ecotoxicology and Environmental Safety, 2021 - Elsevier
Ammonia is a known environmental pollutant that causes injury to the intestine. Growing
evidence suggests that intestinal microbiota dysbiosis involves in the development of …

[HTML][HTML] Organ-organ communication: The liver's perspective

F Wang, KF So, J Xiao, H Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Communication between organs participates in most physiological and pathological events.
Owing to the importance of precise coordination among the liver and virtually all organs in …

[HTML][HTML] The neurogliovascular unit in hepatic encephalopathy

W Claeys, L Van Hoecke, S Lefere, A Geerts… - JHEP reports, 2021 - Elsevier
Hepatic encephalopathy (HE) is a neurological complication of hepatic dysfunction and
portosystemic shunting. It is highly prevalent in patients with cirrhosis and is associated with …

[HTML][HTML] Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

O Braissant, V Rackayová, K Pierzchala, J Grosse… - Journal of …, 2019 - Elsevier
Background & Aims The sequence of events in hepatic encephalopathy (HE) remains
unclear. Using the advantages of in vivo 1H-MRS (9.4 T) we aimed to analyse the time …

Hepatoprotective and cognitive-enhancing effects of hesperidin against thioacetamide-induced hepatic encephalopathy in rats

NFA El-Magd, DH El-Kashef, M El-Sherbiny, SM Eraky - Life Sciences, 2023 - Elsevier
Hepatic encephalopathy (HE) is a serious neurological disorder which might occur in both
acute and chronic liver injury. Aims: This study was carried out to explore the protective …

Syringic acid protects against thioacetamide-induced hepatic encephalopathy: behavioral, biochemical, and molecular evidence

IF Okkay, U Okkay, OL Gundogdu, C Bayram… - Neuroscience …, 2022 - Elsevier
The objective of this study was to elucidate the effects of syringic acid on thioacetamide-
induced hepatic encephalopathy which is a complex serious syndrome with …