Hepatocarcinoma is one of the most prevalent gastroenterological cancers in the world with
less effective therapy. As an oncofetal antigen and diagnostic marker for liver cancer, alpha …

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and shows
high global incidence and mortality rates. The liver is an immune-tolerated organ with a …

A high level of serum alpha fetoprotein (AFP) is positively associated with human
hepatocellular carcinoma (HCC) carcinogenesis and metastasis; however, the function of …

The hepatitis B virus (HBV)-X protein (HBx) induces malignant transformation of liver cells,
and elevated expression of alpha-fetoprotein (AFP) is a significant biomarker of …

Background Recent studies suggest the potential benefits of statins as anti-cancer agents.
Mechanisms by which statins induce apoptosis in cancer cells are not clear. We previously …

The exact influence of statins on gefitinib resistance in human non-small cell lung cancer
(NSCLC) cells with KRAS mutation alone or KRAS/PIK3CA and KRAS/PTEN comutations …

Background & Aims Insulin-like growth factor,(IGF)-1, is produced mainly by the liver and
plays important roles in promoting growth and regulating metabolism. Previous study …

The fifth most common cancer worldwide is hepatocellular carcinoma (HCC), while being
the third leading cause of global cancer-related deaths. Although HCC incidence is less …

Abstract LIM homeobox domain 6 (LHX6) is a putative transcriptional regulator that controls
the differentiation and development of neural and lymphoid cells. However, the function of …

Abstract Background Hepatitis B virus (HBV)-X protein (HBx) is a transactivator of host
several cellular genes including alpha-fetoprotein (AFP) and AFP receptor (AFPR) which …