[HTML][HTML] Inflammatory markers in depression: a meta-analysis of mean differences and variability in 5,166 patients and 5,083 controls

EF Osimo, T Pillinger, IM Rodriguez… - Brain, behavior, and …, 2020 - Elsevier
Importance The magnitude and variability of cytokine alterations in depression are not clear.
Objective To perform an up to date meta-analysis of mean differences of immune markers in …

Peripheral blood cellular immunophenotype in depression: a systematic review and meta-analysis

ÉM Foley, JT Parkinson, RE Mitchell, L Turner… - Molecular …, 2023 - nature.com
Introduction Meta-analyses implicate immune dysfunction in depression confirming
increased levels of circulating immune proteins (eg, cytokines) in depression cases …

A meta-analysis of cytokines in major depression

Y Dowlati, N Herrmann, W Swardfager, H Liu… - Biological …, 2010 - Elsevier
BACKGROUND: Major depression occurs in 4.4% to 20% of the general population. Studies
suggest that major depression is accompanied by immune dysregulation and activation of …

A meta-analysis of differences in IL-6 and IL-10 between people with and without depression: exploring the causes of heterogeneity

SA Hiles, AL Baker, T de Malmanche, J Attia - Brain, behavior, and …, 2012 - Elsevier
Epidemiological evidence for the inflammatory hypothesis of depression is largely cross-
sectional; people with depression have elevated levels of circulating pro-inflammatory …

Higher levels of serum IL-1β and TNF-α are associated with an increased probability of major depressive disorder

R Das, MPZ Emon, M Shahriar, Z Nahar, SMA Islam… - Psychiatry …, 2021 - Elsevier
Major depressive disorder (MDD) is a debilitating psychiatric disease. The dysregulated
cytokines in depression are assumed due to the hyperactivation of the immune system. Here …

Altered serum TNF-α and MCP-4 levels are associated with the pathophysiology of major depressive disorder: A case-control study results

J Nayem, R Sarker, ASM Roknuzzaman, MMAS Qusar… - Plos one, 2023 - journals.plos.org
Background Major Depressive Disorder (MDD) is a debilitating mental health condition with
complex etiology, and recent research has focused on pro-inflammatory cytokines and …

Formononetin improves cardiac function and depressive behaviours in myocardial infarction with depression by targeting GSK-3β to regulate macrophage/microglial …

Y Yang, T Huang, H Zhang, X Li, S Shi, X Tian… - Phytomedicine, 2023 - Elsevier
Background Depression is a common complication after myocardial infarction (MI) that can
seriously affect the prognosis of MI. Purpose To investigate whether formononetin could …

Altered serum interleukin-7 and interleukin-10 are associated with drug-free major depressive disorder

S Anjum, MMAS Qusar, M Shahriar… - Therapeutic …, 2020 - journals.sagepub.com
Background: Abnormal expression of inflammatory cytokines in major depressive disorder
(MDD) suggests the activation of an inflammatory process. The pattern of alterations in …

Circulating cytotoxic T cells and natural killer cells as potential predictors for antidepressant response in melancholic depression. Restoration of T regulatory cell …

L Grosse, LA Carvalho, TK Birkenhager… - …, 2016 - Springer
Rationale There is a substantial unmet need for biomarkers to predict treatment response in
major depressive disorder (MDD). Evidence has converged on activation of the inflammatory …

An act of balance between adaptive and maladaptive immunity in depression: a role for T lymphocytes

C Toben, BT Baune - Journal of Neuroimmune Pharmacology, 2015 - Springer
Historically the monoaminergic neurotransmitter system, in particular the serotonergic
system, was seen as being responsible for the pathophysiology of major depressive …