Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Parvalbumin interneuron vulnerability and brain disorders

JB Ruden, LL Dugan, C Konradi - Neuropsychopharmacology, 2021 - nature.com
Parvalbumin-expressing interneurons (PV-INs) are highly vulnerable to stressors and have
been implicated in many neuro-psychiatric diseases such as schizophrenia, Alzheimer's …

Individual human cortical progenitors can produce excitatory and inhibitory neurons

RN Delgado, DE Allen, MG Keefe, WR Mancia Leon… - Nature, 2022 - nature.com
The cerebral cortex is a cellularly complex structure comprising a rich diversity of neuronal
and glial cell types. Cortical neurons can be broadly categorized into two classes …

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

S Zhong, S Zhang, X Fan, Q Wu, L Yan, J Dong… - Nature, 2018 - nature.com
The mammalian prefrontal cortex comprises a set of highly specialized brain areas
containing billions of cells and serves as the centre of the highest-order cognitive functions …

Cellular transcriptomics reveals evolutionary identities of songbird vocal circuits

BM Colquitt, DP Merullo, G Konopka, TF Roberts… - Science, 2021 - science.org
INTRODUCTION The mammalian neocortex, with its distinctive six-layered structure, is
thought to enable advanced cognitive functions not seen in other animals. Yet birds, which …

Genetic and activity-dependent mechanisms underlying interneuron diversity

B Wamsley, G Fishell - Nature Reviews Neuroscience, 2017 - nature.com
The proper construction of neural circuits requires the generation of diverse cell types, their
distribution to defined regions, and their specific and appropriate wiring. A major objective in …

Interneuron types as attractors and controllers

G Fishell, A Kepecs - Annual review of neuroscience, 2020 - annualreviews.org
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

Decoding the development of the human hippocampus

S Zhong, W Ding, L Sun, Y Lu, H Dong, X Fan, Z Liu… - Nature, 2020 - nature.com
The hippocampus is an important part of the limbic system in the human brain that has
essential roles in spatial navigation and the consolidation of information from short-term …

Interneuron origin and molecular diversity in the human fetal brain

Y Yu, Z Zeng, D Xie, R Chen, Y Sha, S Huang… - Nature …, 2021 - nature.com
Precise generation of excitatory neurons and inhibitory interneurons is crucial for proper
formation and function of neural circuits in the mammalian brain. Because of the size and …

[HTML][HTML] The BRAIN initiative cell census consortium: lessons learned toward generating a comprehensive brain cell atlas

JR Ecker, DH Geschwind, AR Kriegstein, J Ngai… - Neuron, 2017 - cell.com
A comprehensive characterization of neuronal cell types, their distributions, and patterns of
connectivity is critical for understanding the properties of neural circuits and how they …