WW Pang, SL Schrier, IL Weissman - Seminars in hematology, 2017 - Elsevier
Aging has a broad impact on the function of the human hematopoietic system. This review will focus primarily on the effect of aging on the human hematopoietic stem cell (HSC) …
Donor selection contributes to improve clinical outcomes of T-cell–replete haploidentical stem cell transplantation (haplo-SCT) with posttransplant cyclophosphamide (PT-Cy). The …
VE Kennedy, RL Olin - The Lancet Haematology, 2021 - thelancet.com
Haematopoietic stem-cell transplantation (HSCT) has seen substantial growth among older adults. Chronological age is no longer viewed as an absolute barrier to HSCT, and …
R Tarazona, N Lopez-Sejas, B Guerrero… - Cancer Immunology …, 2020 - Springer
A better understanding of the complex interactions between the immune system and tumour cells from different origins has opened the possibility to design novel procedures of …
MP Pereira, M Remberger, C Chen, A Gerbitz… - … and Cellular Therapy, 2023 - Elsevier
The choice between an older matched sibling donor (MSD) and a younger matched unrelated donor (MUD) in allogeneic hematopoietic cell transplantation (HCT) remains a …
Highlights•MSC senescence poses a major challenge in regenerative application.• Senotherapeutics could overcome MSC senescence during in vitro expansion.• …
We compared transplantation (HSCT) outcomes in AML patients undergoing HSCT with post- transplant cyclophosphamide (PTCy) in first complete remission from 1065 young (< 35 …
R Reshef, AP Huffman, A Gao, MR Luskin… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To characterize the impact of graft T-cell composition on outcomes of reduced- intensity conditioned (RIC) allogeneic hematopoietic stem-cell transplantation (alloHSCT) in …
C Niederwieser, E Morozova, L Zubarovskaya… - Bone Marrow …, 2021 - nature.com
Allogeneic hematopoietic stem-cell transplantation (HSCT) remains the only curative option for patients with advanced chronic myeloid leukemia (CML). However, outcome is dismal …