Nociception is an important physiological process that detects harmful signals and results in
pain perception. In this review, we discuss important experimental evidence involving some …

Over two hundred billion black soldier flies (BSF, Hermetia illucens (Diptera: Stratiomyidae))
are reared annually across the globe, with the industry projected to grow substantially in the …

Sentience–the ability to feel, perceive and experience–is central to the animal welfare
debate as it raises the question of whether animals experience suffering in life and death …

Abstract The Transient Receptor Potential Ankyrin 1 channel (TRPA1), is a member of the
large TRP family of ion channels, and functions as a Ca 2+ permeable non-selective cation …

Chronic pain is a maladaptive neurological disease that remains a major health problem. A
deepening of our knowledge on mechanisms that cause pain is a prerequisite to developing …

Genetic approaches in the fruit fly, Drosophila melanogaster, have led to a major triumph in
the field of sensory biology—the discovery of multiple large families of sensory receptors …

Specialized somatosensory neurons detect temperatures ranging from pleasantly cool or
warm to burning hot and painful (nociceptive). The precise temperature ranges sensed by …

The functions of TRP channels have primarily been characterized in model organisms within
a limited evolutionary context. We thus characterize the TRP channels in choanoflagellate …

Injury can lead to devastating and often untreatable chronic pain. While acute pain
perception (nociception) evolved more than 500 million years ago, virtually nothing is known …

Multiple classes of cell surface receptors and ion channels participate in the detection of
changes in environmental stimuli, and thereby influence animal behavior. Among the many …