Current and promising pharmacotherapeutic options for candidiasis
L Scorzoni, BB Fuchs, JC Junqueira… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: Candida spp. are commensal yeasts capable of causing infections such as
superficial, oral, vaginal, or systemic infections. Despite medical advances, the antifungal …
superficial, oral, vaginal, or systemic infections. Despite medical advances, the antifungal …
Dissecting the anti-biofilm potency of kappa-carrageenan capped silver nanoparticles against Candida species
Global antimicrobial crisis and advent of drug resistant fungal strains has substantially
distressed disease management for clinicians. Biodegradable silver nanoparticles (AgNps) …
distressed disease management for clinicians. Biodegradable silver nanoparticles (AgNps) …
Effectiveness of Phytoactive Molecules on Transcriptional Expression, Biofilm Matrix, and Cell Wall Components of Candida glabrata and Its Clinical Isolates
Toxicity challenges by antifungal arsenals and emergence of multidrug resistance scenario
has posed a serious threat to global community. To cope up with this alarming situation …
has posed a serious threat to global community. To cope up with this alarming situation …
Geraniol eradicates Candida glabrata biofilm by targeting multiple cellular pathways
Global burden of fungal infections and associated health risk has accelerated at an
incredible pace and needs to be attended at the earliest with an unbeatable therapeutic …
incredible pace and needs to be attended at the earliest with an unbeatable therapeutic …
Mechanistic insights into Candida biofilm eradication potential of eucalyptol
Aim Candida‐associated fungal infections are prevalent in hospitalized and immune‐
compromised patients. Their biofilm architecture and high rate of antifungal resistance make …
compromised patients. Their biofilm architecture and high rate of antifungal resistance make …
Assessing the eradication potential of fungal biofilms using acacia gum/PVA nanofibers functionalized with geraniol-β cyclodextrin inclusion complex
The world is witnessing severe fungal co-infections with incidences of antifungal resistance
and increased morbidity/mortality. The present study is focused on fabricating geraniol …
and increased morbidity/mortality. The present study is focused on fabricating geraniol …
Molecular investigations on Candida glabrata clinical isolates for pharmacological targeting
Prevalence of drug resistant C. glabrata strains in hospitalized immune-compromised
patients with invasive fungal infections has increased at an unexpected pace. This has …
patients with invasive fungal infections has increased at an unexpected pace. This has …
Amlodipine and lufenuron as repurposing drugs against Sporothrix brasiliensis
VR Poester, JED Hidalgo, LS Jardim, MR Trápaga… - PeerJ, 2023 - peerj.com
Background Sporotrichosis caused by Sporothrix brasiliensis is a globally emerging
infectious disease with limited therapeutic options. Thus, we aimed to evaluate the in vitro …
infectious disease with limited therapeutic options. Thus, we aimed to evaluate the in vitro …
Elucidating the lactic acid tolerance mechanism in vaginal clinical isolates of Candida glabrata
Incidence of vulvovaginal candidiasis are strikingly high and treatment options are limited
with nearly 50% Candida glabrata cases left untreated or experience treatment failures. The …
with nearly 50% Candida glabrata cases left untreated or experience treatment failures. The …
Functional characterization of Candida glabrata ORF, CAGL0M02233g for its role in stress tolerance and virulence
Present investigation is aimed to analyze the role of an uncharacterized ORF of Candida
glabrata (CBS138), CAGL0M02233g (an ortholog of RAD53, a key DNA checkpoint effector …
glabrata (CBS138), CAGL0M02233g (an ortholog of RAD53, a key DNA checkpoint effector …