Allogeneic natural killer cell therapy
Interest in adoptive cell therapy for treating cancer is exploding owing to early clinical
successes of autologous chimeric antigen receptor (CAR) T lymphocyte therapy. However …
successes of autologous chimeric antigen receptor (CAR) T lymphocyte therapy. However …
Neoantigens: promising targets for cancer therapy
Recent advances in neoantigen research have accelerated the development and regulatory
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …
Direct Presentation of Tumor‐Associated Antigens to Induce Adaptive Immunity by Personalized Dendritic Cell‐Mimicking Nanovaccines
Dendritic cells (DCs)‐based vaccines are an approved method for inducing potent antigen‐
specific immune responses to eliminate tumor cells. However, this promising strategy still …
specific immune responses to eliminate tumor cells. However, this promising strategy still …
Current status and future perspectives in targeted therapy of NPM1-mutated AML
Abstract Nucleophosmin 1 (NPM1) is a nucleus-cytoplasmic shuttling protein which is
predominantly located in the nucleolus and exerts multiple functions, including regulation of …
predominantly located in the nucleolus and exerts multiple functions, including regulation of …
[HTML][HTML] NK cell-based tumor immunotherapy
H Zhang, L Yang, T Wang, Z Li - Bioactive materials, 2024 - Elsevier
Natural killer (NK) cells display a unique inherent ability to identify and eliminate virus-
infected cells and tumor cells. They are particularly powerful for elimination of hematological …
infected cells and tumor cells. They are particularly powerful for elimination of hematological …
Development of NK cell-based cancer immunotherapies through receptor engineering
A Page, N Chuvin, J Valladeau-Guilemond… - Cellular & Molecular …, 2024 - nature.com
Natural killer (NK) cell-based immunotherapies are attracting increasing interest in the field
of cancer treatment. Early clinical trials have shown promising outcomes, alongside …
of cancer treatment. Early clinical trials have shown promising outcomes, alongside …
CAR-T and CAR-NK as cellular cancer immunotherapy for solid tumors
In the past decade, chimeric antigen receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach for combating cancers, demonstrating remarkable …
promising immunotherapeutic approach for combating cancers, demonstrating remarkable …
Overcoming tumor resistance mechanisms in CAR-NK cell therapy
A Valeri, A García-Ortiz, E Castellano… - Frontiers in …, 2022 - frontiersin.org
Despite the impressive results of autologous CAR-T cell therapy in refractory B
lymphoproliferative diseases, CAR-NK immunotherapy emerges as a safer, faster, and cost …
lymphoproliferative diseases, CAR-NK immunotherapy emerges as a safer, faster, and cost …
Chimeric antigen receptor engineered natural killer cells for cancer therapy
Y Zhang, W Zhou, J Yang, J Yang, W Wang - Experimental Hematology & …, 2023 - Springer
Natural killer (NK) cells, a unique component of the innate immune system, are inherent
killers of stressed and transformed cells. Based on their potent capacity to kill cancer cells …
killers of stressed and transformed cells. Based on their potent capacity to kill cancer cells …
[HTML][HTML] IPSC-derived CAR-NK cells for cancer immunotherapy
X Lin, Y Sun, X Dong, Z Liu, R Sugimura… - Biomedicine & …, 2023 - Elsevier
Adoptive cell therapies (ACT) based on chimeric antigen receptor (CAR)-modified immune
cells have made great progress with six CAR-T cell products approved by the US FDA for …
cells have made great progress with six CAR-T cell products approved by the US FDA for …