Chemical and biological evaluation of thiosemicarbazone-bearing heterocyclic metal complexes

AI Matesanz, JM Herrero… - Current topics in medicinal …, 2021 - ingentaconnect.com
Thiosemicarbazones (TSCNs) constitute a broad family of compounds (R1R2C= N-NH-C (S)-
NR3R4), particularly attractive because many of them display some biological activity …

α-N-heterocyclic thiosemicarbazone derivatives as potential antitumor agents: a structure-activity relationships approach

AI Matesanz, P Souza - Mini reviews in medicinal chemistry, 2009 - benthamdirect.com
α-N-Heterocyclic thiosemicarbazones,(N)-TSCs, are potent inhibitors of ribonucleotide
reductase (RR). This enzyme plays a critical role in DNA synthesis and repair, and is a well …

Mn (II), Co (II) and Zn (II) complexes with heterocyclic substituted thiosemicarbazones: Synthesis, characterization, X-ray crystal structures and antitumor comparison

MX Li, CL Chen, D Zhang, JY Niu, BS Ji - European Journal of Medicinal …, 2010 - Elsevier
Transition metal complexes Mn (L1) 2 (1), Mn (L2) 2 (2), Co (L3) 2Cl 4H2O (3), Zn (L3) 2
DMF (4), Co (HL4) 2 (ClO4) 2 3H2O (5) and Zn (L5) 2 DMF (6) where HL1= 2-acetylpyridine …

Influence of terminal substitution on structural, DNA, protein binding, anticancer and antibacterial activities of palladium (II) complexes containing 3-methoxy …

P Kalaivani, R Prabhakaran, E Ramachandran… - Dalton …, 2012 - pubs.rsc.org
The variable chelating behavior of 3-methoxysalicylaldehyde-4 (N)-substituted
thiosemicarbazones was observed in equimolar reactions with [PdCl2 (PPh3) 2]. The new …

Copper complexes of imidazole-2-, pyrrole-2-and indol-3-carbaldehyde thiosemicarbazones: inhibitory activity against fungi and bacteria

MC Rodríguez-Argüelles, EC López-Silva… - Journal of inorganic …, 2005 - Elsevier
Copper complexes of thiosemicarbazones of imidazole-2-carbaldehyde, pyrrole-2-
carbaldehyde and indole-3-carbaldehyde were synthesised and characterised. The …

Synthesis, spectral, thermal and antimicrobial studies on cobalt (II), nickel (II), copper (II), zinc (II) and palladium (II) complexes containing thiosemicarbazone ligand

AK El-Sawaf, F El-Essawy, AA Nassar… - Journal of Molecular …, 2018 - Elsevier
The coordination characteristic of new N 4-morpholinyl isatin-3-thiosemicarbazone (HL)
towards Co (II), Ni (II), Cu (II), Zn (II) and Pd (II) has been studies. The structures of the …

Evaluation of DNA binding, antioxidant and cytotoxic activity of mononuclear Co (III) complexes of 2-oxo-1, 2-dihydrobenzo [h] quinoline-3-carbaldehyde …

E Ramachandran, SP Thomas, P Poornima… - European journal of …, 2012 - Elsevier
Four new 2-oxo-1, 2-dihydrobenzo [h] quinoline-3-carbaldehyde N-substituted
thiosemicarbazone ligands (H2-LR, where R= H, Me, Et or Ph) and their corresponding new …

Spectral, Magnetic, Electrical and Thermal Studies on Malonyl bis(thiosemicarbazide) Complexes

NM El-Metwally, IM Gabr, AA El-Asmy… - Transition Metal …, 2006 - Springer
Mono-and binuclear complexes of malonyl bis (thiosemicarbazide), H 4 MBT, with VO 2+,
Co 2+, Ni 2+, Cu 2+, Cd 2+ and Pt 4+ have been isolated. The elemental analyses, magnetic …

Co (III), Ni (II), Zn (II) and Cd (II) complexes with 2-acetyl-2-thiazoline thiosemicarbazone: Synthesis, characterization, X-ray structures and antibacterial activity

E Viñuelas-Zahínos, F Luna-Giles… - European journal of …, 2011 - Elsevier
The new ligand 2-acetyl-2-thiazoline thiosemicarbazone (HATtsc) and the complexes [Co
(ATtsc) 2] 2 [CoCl4]· 2H2O (1),[Co (ATtsc) 2] NO3· H2O (2),[Ni (HATtsc) 2](NO3) 2 (3),[ZnCl2 …

Complexes of 2-acetyl-γ-butyrolactone and 2-furancarbaldehyde thiosemicarbazones: antibacterial and antifungal activity

MC Rodríguez-Argüelles, P Tourón-Touceda… - Journal of Inorganic …, 2009 - Elsevier
Cobalt, nickel, copper and zinc coordination compounds of two thiosemicarbazones with
general composition ML2 (L: monodeprotonated ligand corresponding to 2-acetyl-γ …