Halogenated antimicrobial agents to combat drug-resistant pathogens

OS Faleye, BR Boya, JH Lee, I Choi, J Lee… - Pharmacological …, 2024 - Elsevier
Antimicrobial resistance presents us with a potential global crisis as it undermines the
abilities of conventional antibiotics to combat pathogenic microbes. The history of …

Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Antimalarial application of quinones: A recent update

OPS Patel, RM Beteck, LJ Legoabe - European Journal of Medicinal …, 2021 - Elsevier
Atovaquone belongs to a naphthoquinone class of drugs and is used in combination with
proguanil (Malarone) for the treatment of acute, uncomplicated malaria caused by …

Thymoquinone, as a novel therapeutic candidate of cancers

B Almajali, HAN Al-Jamal, WRW Taib, I Ismail… - Pharmaceuticals, 2021 - mdpi.com
To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …

Importance of thymoquinone, sulforaphane, phloretin, and epigallocatechin and their health benefits

MH Shahrajabian, W Sun - Letters in Drug Design & Discovery, 2024 - benthamdirect.com
Natural products have a broad diversity of multidimensional chemical formations, which play
an important role, and indicate the crucial nature as a golden source for gaining herbal drug …

Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical …

J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …

Discovery and development of botanical natural products and their analogues as therapeutics for ovarian cancer

BK Mize, A Salvi, Y Ren, JE Burdette… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2015 through the end of July 2022 Ovarian cancer is one of the most common
cancers affecting the female reproductive organs and has the highest mortality rate among …

Therapeutic perspectives of the black cumin component thymoquinone: A review

C Sarkar, S Jamaddar, T Islam, M Mondal, MT Islam… - Food & Function, 2021 - pubs.rsc.org
The dietary phytochemical thymoquinone (TQ), belonging to the family of quinones, mainly
obtained from the black and angular seeds of Nigella sativa, is one of the promising …

A quinquennial review on recent advancements and developments in search of anti-malarial agents

TM Dhameliya, D Kathuria, TM Patel… - Current Topics in …, 2023 - benthamdirect.com
Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

In vitro and in vivo antimalarial activity and chemical profiling of sugarcane leaves

JE Okokon, R Mobley, UA Edem, AI Bassey… - Scientific Reports, 2022 - nature.com
Abstract Saccharum officinarum Linn.(sugarcane, Family-Poaceae) is employed in Ibibio
traditional medicine for the treatment of various infections and diseases such as malaria. We …