Current and future development in lung cancer diagnosis
R Nooreldeen, H Bach - International journal of molecular sciences, 2021 - mdpi.com
Lung cancer is the leading cause of cancer-related deaths in North America and other
developed countries. One of the reasons lung cancer is at the top of the list is that it is often …
developed countries. One of the reasons lung cancer is at the top of the list is that it is often …
[HTML][HTML] Biomarkers in lung cancer screening: achievements, promises, and challenges
The present review is an update of the research and development efforts regarding the use
of molecular biomarkers in the lung cancer screening setting. The two main unmet clinical …
of molecular biomarkers in the lung cancer screening setting. The two main unmet clinical …
[HTML][HTML] A proteogenomic portrait of lung squamous cell carcinoma
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …
DNA methylation arrays as surrogate measures of cell mixture distribution
EA Houseman, WP Accomando, DC Koestler… - BMC …, 2012 - Springer
Background There has been a long-standing need in biomedical research for a method that
quantifies the normally mixed composition of leukocytes beyond what is possible by simple …
quantifies the normally mixed composition of leukocytes beyond what is possible by simple …
Epidemiology of lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines
AJ Alberg, MV Brock, JG Ford, JM Samet, SD Spivack - Chest, 2013 - Elsevier
Background Ever since a lung cancer epidemic emerged in the mid-1900s, the
epidemiology of lung cancer has been intensively investigated to characterize its causes …
epidemiology of lung cancer has been intensively investigated to characterize its causes …
The potential of using blood circular RNA as liquid biopsy biomarker for human diseases
Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …
Exosomes as divine messengers: are they the Hermes of modern molecular oncology?
C Braicu, C Tomuleasa, P Monroig… - Cell Death & …, 2015 - nature.com
Exosomes are cell-derived vesicles that convey key elements with the potential to modulate
intercellular communication. They are known to be secreted from all types of cells, and are …
intercellular communication. They are known to be secreted from all types of cells, and are …
Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome
The impact of cigarette smoking can persist for extended periods following smoking
cessation and may involve epigenetic reprogramming. Changes in DNA methylation …
cessation and may involve epigenetic reprogramming. Changes in DNA methylation …
Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis
JD Herazo-Maya, I Noth, SR Duncan, SH Kim… - Science translational …, 2013 - science.org
We aimed to identify peripheral blood mononuclear cell (PBMC) gene expression profiles
predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) by performing microarray …
predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) by performing microarray …
[HTML][HTML] miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer
Introduction: The ability to diagnose non-small cell lung cancer (NSCLC) at an early stage
may lead to improved survival. The aim of this study was to identify differentially expressed …
may lead to improved survival. The aim of this study was to identify differentially expressed …