Aptamer in bioanalytical applications

AB Iliuk, L Hu, WA Tao - Analytical chemistry, 2011 - ACS Publications
(2009À2010), thefield of aptamer research has continuously generated lots of interest in the
scientific community. Aptamers, first reported by three groups independently in 1990, 1À3 …

Selection and biosensor application of aptamers for small molecules

F Pfeiffer, G Mayer - Frontiers in chemistry, 2016 - frontiersin.org
Small molecules play a major role in the human body and as drugs, toxins, and chemicals.
Tools to detect and quantify them are therefore in high demand. This review will give an …

Pushing adenosine and ATP SELEX for DNA aptamers with nanomolar affinity

Y Ding, J Liu - Journal of the American Chemical Society, 2023 - ACS Publications
The classical DNA aptamer for adenosine and ATP has been the most used small molecule
binding aptamer for biosensing, imaging, and DNA nanotechnology. This sequence has …

Nucleic‐acid structures as intracellular probes for live cells

D Samanta, SB Ebrahimi, CA Mirkin - Advanced Materials, 2020 - Wiley Online Library
The chemical composition of cells at the molecular level determines their growth,
differentiation, structure, and function. Probing this composition is powerful because it …

Release of extracellular ATP by bacteria during growth

R Mempin, H Tran, C Chen, H Gong, K Kim Ho, S Lu - BMC microbiology, 2013 - Springer
Background Adenosine triphosphate (ATP) is used as an intracellular energy source by all
living organisms. It plays a central role in the respiration and metabolism, and is the most …

Aptamers in analytics

M Ilgu, M Nilsen-Hamilton - Analyst, 2016 - pubs.rsc.org
Nucleic acid aptamers are promising alternatives to antibodies in analytics. They are
generally obtained through an iterative SELEX protocol that enriches a population of …

Intracellular ATP concentration and implication for cellular evolution

JV Greiner, T Glonek - Biology, 2021 - mdpi.com
Simple Summary The lens organ of the eye and muscle tissue exist at opposite ends of the
metabolic spectrum. Lens is metabolically quiescent using little energy, while muscle has …

Organelle-based aggregation and retention of damaged proteins in asymmetrically dividing cells

C Zhou, BD Slaughter, JR Unruh, F Guo, Z Yu… - Cell, 2014 - cell.com
Aggregation of damaged or misfolded proteins is a protective mechanism against
proteotoxic stress, abnormalities of which underlie many aging-related diseases. Here, we …

A glucose-starvation response regulates the diffusion of macromolecules

RP Joyner, JH Tang, J Helenius, E Dultz, C Brune… - elife, 2016 - elifesciences.org
The organization and biophysical properties of the cytosol implicitly govern molecular
interactions within cells. However, little is known about mechanisms by which cells regulate …

Ca2+ Regulation of Mitochondrial ATP Synthesis Visualized at the Single Cell Level

M Nakano, H Imamura, T Nagai, H Noji - ACS chemical biology, 2011 - ACS Publications
Intracellular Ca2+ levels play a crucial role in the control of ATP synthesis. However, the
spatiotemporal correlation between ATP and Ca2+ remains unclear due to the inability to …