Abnormal placentation is considered as an underlying cause of various pregnancy
complications such as miscarriage, preeclampsia and intrauterine growth restriction, the …

Correct development of the human placenta and its differentiated epithelial cells, syncytial
trophoblasts (STBs) and extravillous trophoblasts (EVTs), is crucial for a successful …

Defective placentation is the underlying cause of various pregnancy complications, such as
severe intrauterine growth restriction and preeclampsia. However, studies on human …

During pregnancy the maternal–fetal interface plays vital roles in fetal development. Its
disruption is frequently found in pregnancy complications. Recent studies show increased …

Early pregnancy loss affects∼ 15% of all implantation-confirmed human conceptions.
However, evolutionarily conserved molecular mechanisms that regulate self-renewal of …

Ruminants have a semi-invasive placenta, which possess highly vascularized placentomes
formed by maternal endometrial caruncles and fetal placental cotyledons and required for …

In humans, cell fusion is restricted to only a few cell types under normal conditions. In the
placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant …

The placenta is an organ with extraordinary phenotypic diversity in eutherian mammals.
Recent evidence suggests that numerous human placental enhancers are evolved from …

The placenta is an essential organ that supports the growth and development of the fetus
during pregnancy. However, cell type-specific enhancers and transcription factors (TFs), and …

Pregnancy and parturition are intricately regulated to ensure successful reproductive
outcomes. However, the factors that control gestational length in humans and other …