Mammalian stress granules and P bodies at a glance

CL Riggs, N Kedersha, P Ivanov… - Journal of cell …, 2020 - journals.biologists.com
Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-
based cellular compartments that assemble in response to stress. SGs and PBs form …

Stress granules and processing bodies in translational control

P Ivanov, N Kedersha… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Stress granules (SGs) and processing bodies (PBs) are non-membrane-enclosed RNA
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …

The integral role of RNA in stress granule formation and function

D Campos-Melo, ZCE Hawley… - Frontiers in Cell and …, 2021 - frontiersin.org
Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein
(RNP) assemblies whose primary function is to promote cell survival by condensing …

[HTML][HTML] Cytoplasmic stress granules: Dynamic modulators of cell signaling and disease

H Mahboubi, U Stochaj - Biochimica et Biophysica Acta (BBA)-Molecular …, 2017 - Elsevier
Stress granule (SG) assembly is a conserved cellular strategy to minimize stress-related
damage and promote cell survival. Beyond their fundamental role in the stress response …

Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion

M Galasso, JJ Feld, Y Watanabe, M Pipkin… - Nature …, 2019 - nature.com
Availability of organs is a limiting factor for lung transplantation, leading to substantial
mortality rates on the wait list. Use of organs from donors with transmissible viral infections …

Stress granule subtypes: an emerging link to neurodegeneration

VM Advani, P Ivanov - Cellular and Molecular Life Sciences, 2020 - Springer
Abstract Stress Granules (SGs) are membraneless cytoplasmic RNA granules, which
contain translationally stalled mRNAs, associated translation initiation factors and multiple …

Stress granules and hormetic adaptation of cancer

A Redding, E Grabocka - Trends in Cancer, 2023 - cell.com
Cell stress is inherent to cancer and a key driver of tumorigenesis. Recent studies have
proposed that cell stress promotes tumorigenesis through non-membranous organelles …

Aberrant phase transitions: side effects and novel therapeutic strategies in human disease

V Verdile, E De Paola, MP Paronetto - Frontiers in genetics, 2019 - frontiersin.org
Phase separation is a physiological process occurring spontaneously when single-phase
molecular complexes separate in two phases, a concentrated phase and a more diluted …

[HTML][HTML] Stress granules inhibit fatty acid oxidation by modulating mitochondrial permeability

T Amen, D Kaganovich - Cell reports, 2021 - cell.com
The formation of stress granules (SGs) is an essential aspect of the cellular response to
many kinds of stress, but its adaptive role is far from clear. SG dysfunction is implicated in …

Relocalization of translation termination and ribosome recycling factors to stress granules coincides with elevated stop-codon readthrough and reinitiation rates upon …

DS Makeeva, CL Riggs, AV Burakov, PA Ivanov… - Cells, 2023 - mdpi.com
Upon oxidative stress, mammalian cells rapidly reprogram their translation. This is
accompanied by the formation of stress granules (SGs), cytoplasmic ribonucleoprotein …