Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

The pace of bone formation slows down with aging, which leads to the development of
osteoporosis. In addition to senescent bone marrow mesenchymal stem cells (S-BMSCs) …

The musculoskeletal system supports the movement of the entire body and provides blood
production while acting as an endocrine organ. With aging, the balance of bone …

Life expectancy and age-related diseases burden increased significantly over the past few
decades. Age-related conditions are commonly discussed in a very limited paradigm of …

With the global increase of the elderly population, the improvement of the treatment for
various aging-related diseases and the extension of a healthy lifespan have become some …

In cell transplantation therapy, mesenchymal stem cells (MSCs) are ideal seed cells due to
their easy acquisition and cultivation, strong regenerative capacity, multi-directional …

Cellular senescence is a cell cycle arrest in damaged or aged cells. Although this represents
a critical mechanism of tumor suppression, persistence of senescent cells during aging …

Mesenchymal stromal cells (MSCs) are a heterogenous cell population found in a wide
range of tissues in the body, known for their nutrient-producing and immunomodulatory …