Virtually all glioblastomas treated in the first-line setting will recur in a short period of time,
and the search for alternative effective treatments has so far been unsuccessful. Various …

Cellular senescence is a state of permanent growth arrest. It can be triggered by telomere
shortening (replicative senescence) or prematurely induced by stresses such as DNA …

Herein, we design a rGO-based magnetic nanocomposite by decorating rGO with citrate-
coated magnetic nanoparticles (CMNP). The magnetic rGO (mrGO) was modified by …

Background Adipose-derived stem cells (ADSC) are multipotent cells implicated in tissue
homeostasis. Obesity represents a chronic inflammatory disease associated with metabolic …

Aim 68 Ga-RM2 is a bombesin (BBN) analog that targets the gastrin releasing peptide
receptors (GRPR) overexpressed in many cancer cells, including prostate cancer (PC). It …

G-protein-coupled receptors (GPCRs) are increasingly being considered as possible
therapeutic targets in cancers. Activation of GPCR on tumors can have prominent growth …

Background Current experimental models using either human or mouse cell lines, are not
representative of the complex features of GBM. In particular, there is no model to study …

Neuroblastoma (NB) is the most common extracranial solid childhood tumor accounting for
around 15% of pediatric cancer deaths and most probably originates from a failure in the …

Glioblastoma (GB) is the most lethal form of primary brain neoplasm. TMZ is the first-line
standard treatment, but the strong resistance constrains the efficacy in clinical use. GB …

Several important biological roles of BLPs and their receptors in nervous system were
identified. Together with researches regarding central roles of BLPs, studies revealing the …