Neuropeptide Y peptide family and cancer: Antitumor therapeutic strategies

ML Sánchez, FD Rodríguez, R Coveñas - International Journal of …, 2023 - mdpi.com
Currently available data on the involvement of neuropeptide Y (NPY), peptide YY (PYY), and
pancreatic polypeptide (PP) and their receptors (YRs) in cancer are updated. The structure …

Obesity-related gut hormones and cancer: Novel insight into the pathophysiology

MA Guzzardi, G Pugliese, F Bottiglieri… - International Journal of …, 2021 - nature.com
The number of cancers attributed to obesity is increasing over time. The mechanisms
classically implicated in cancer pathogenesis and progression in patients with obesity …

Identification and verification of core genes in colorectal cancer

H Xu, Y Ma, J Zhang, J Gu, X Jing, S Lu… - BioMed Research …, 2020 - Wiley Online Library
Colorectal cancer, a malignant neoplasm that occurs in the colorectal mucosa, is one of the
most common types of gastrointestinal cancer. Colorectal cancer has been studied …

Darpp-32: a Novel Antiapoptotic Gene in Upper Gastrointestinal Carcinomas

A Belkhiri, A Zaika, N Pidkovka, S Knuutila, C Moskaluk… - Cancer research, 2005 - AACR
We show the molecular mechanisms involved in Darpp-32 overexpression and its biological
role in upper gastrointestinal adenocarcinomas (UGC). A tumor tissue array of 377 samples …

Relevance of the neuropeptide Y system in the biology of cancer progression

M Ruscica, E Dozio, M Motta… - Current topics in …, 2007 - ingentaconnect.com
The peptides pancreatic polypeptide (PP), peptide YY (PYY), and neuropeptide Y (NPY)
share a similar structure, known as PP-fold. Within this family of peptides, NPY, a highly …

Peptide YY and cancer: current findings and potential clinical applications

WW Tseng, CD Liu - Peptides, 2002 - Elsevier
Peptide YY (PYY) is a naturally occurring gut hormone with mostly inhibitory actions on
multiple tissue targets. PYY has been identified in several carcinoid tumors and a decreased …

in vitro Biological Evaluation of Folate‐Functionalized Block Copolymer Micelles for Selective Anti‐Cancer Drug Delivery

M Licciardi, EF Craparo, G Giammona… - Macromolecular …, 2008 - Wiley Online Library
The main objective of this study was to evaluate the ability of folic acid‐functionalized
diblock copolymer micelles to improve the delivery and uptake of two poorly water‐soluble …

[HTML][HTML] PYY modulates the tumorigenesis and progression of colorectal cancer unveiled by proteomics

F Jing, G Liu, R Zhang, W Xue, J Lin, H Zhu… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Despite decrease in mortality caused by colorectal cancer (CRC), there remains no effective
therapeutic method for patients with CRC. We attempted to screen biomarkers with …

Mitochondria permeabilization by a novel polycation peptide BTM-P1

VV Lemeshko, M Arias, S Orduz - Journal of Biological Chemistry, 2005 - ASBMB
Bacillus thuringiensis subsp. medellin is known to produce the Cry11Bb protein of 94 kDa,
which is toxic for mosquito larvae due to permeabilization of the plasma membrane of …

Peptide YY inhibits the growth of Barrett's esophageal adenocarcinoma in vitro

DW McFadden, DR Riggs, BJ Jackson… - The American journal of …, 2004 - Elsevier
BACKGROUND: Peptide YY (PYY) is an endogenous gut hormone that inhibits the growth of
certain cancers. Adenocarcinoma of the esophagus usually arises from Barrett's esophagus …