Summary Abstract Tocilizumab (RoActemra® or Actemra®) is a recombinant humanized
monoclonal antibody that acts as an interleukin (IL)-6 receptor antagonist. Intravenous …

Since the dawn of civilization, elemental gold and gold compounds have been revered and
utilized by Shamen and medical practitioners alike for many varied pathological problems. In …

TNF-α has been found to play a pivotal role in the pathogenic mechanisms of rheumatoid
arthritis (RA). Drugs targeting TNF-α have been developed to neutralise the deleterious …

OBJETIVOS: O presente estudo teve por objetivo descrever o processo de implementação
de um registro nacional em um país em desenvolvimento (Brasil) e relatar os principais …

Chris Deighton1, Kimme Hyrich2, Tina Ding1, Jo Ledingham3, Mark Lunt2, Raashid
Luqmani4, Patrick Kiely5, Marwan Bukhari6, Rikki Abernethy7, Andrew Ostor8, Ailsa …

Objective: To assess the workplace costs of rheumatoid arthritis (RA) from the employer
perspective. Method: Samples included 4485 manufacturing firm (MF) employees (109 with …

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease. In the majority of
patients the course is progressive and leads to destruction of joints, functional disability …

Objectives: To suppress rheumatoid arthritis (RA) patients' disease activity, it should be
periodically measured and patients should be treated on the basis of the disease activity …

Objective Assessor‐based disease activity measures such as the Disease Activity Score in
28 joints (DAS28), although widely used in rheumatoid arthritis (RA), have high …

The association of opportunistic infections in the context of anti-tumor necrosis factor (TNF)
antibody therapies have attracted widespread attention. The recent H1N1 influenza …