A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes
S Yang, C Liu, M Jiang, X Liu, L Geng, Y Zhang… - Protein & …, 2024 - academic.oup.com
Aging increases the risk of liver diseases and systemic susceptibility to aging-related
diseases. However, cell type-specific changes and the underlying mechanism of liver aging …
diseases. However, cell type-specific changes and the underlying mechanism of liver aging …
[HTML][HTML] Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study
Prior observational studies suggest an association between intra-pancreatic fat deposition
(IPFD) and pancreatic ductal adenocarcinoma (PDAC); however, the causal relationship is …
(IPFD) and pancreatic ductal adenocarcinoma (PDAC); however, the causal relationship is …
Whole-genome sequencing of half-a-million UK Biobank participants
UK Biobank Whole-Genome Sequencing Consortium… - medRxiv, 2023 - medrxiv.org
Whole-genome sequencing (WGS) provides a comprehensive view of the genome, enabling
detection of coding and non-coding genetic variation, and surveying complex regions which …
detection of coding and non-coding genetic variation, and surveying complex regions which …
[HTML][HTML] Is increased myocardial triglyceride content associated with early changes in left ventricular function? A 1H-MRS and MRI strain study
A Soghomonian, A Dutour, N Kachenoura… - Frontiers in …, 2023 - frontiersin.org
Background Type 2 diabetes (T2D) and obesity induce left ventricular (LV) dysfunction. The
underlying pathophysiological mechanisms remain unclear, but myocardial triglyceride …
underlying pathophysiological mechanisms remain unclear, but myocardial triglyceride …
Reassessing the causal relationship between liver diseases and cardiovascular outcomes
X Xiang, Y Wei, K Zhao - Journal of Hepatology, 2024 - journal-of-hepatology.eu
To the Editor, We read with great interest the study by Roca-Fernandez et al. which revealed
the Liver disease activity (measured by iron corrected T1-mapping (cT1)) was independently …
the Liver disease activity (measured by iron corrected T1-mapping (cT1)) was independently …