Post-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested
in clinical symptoms that develop and persist in patients during and/or after discontinuing …

Steroids are important physiological orchestrators of endocrine as well as peripheral and
central nervous system functions. One of the key processes for regulation of these molecules …

Objective: Finasteride, a commonly prescribed medication for male pattern hair loss, has
recently been associated with persistent sexual side effects. In addition, depression has …

Recent reports show that, in patients treated with finasteride for male pattern hair loss,
persistent side effects including sexual side effects, depression, anxiety and cognitive …

ABSTRACT Introduction 5α-Reductase inhibitors (5ARIs) are widely used for the treatment
of benign prostatic hyperplasia (BPH) and androgenetic alopecia (AGA). Aim To review all …

With aging, abnormal benign growth of the prostate results in benign prostate hyperplasia
(BPH) with concomitant lower urinary tract symptoms (LUTS). Because the prostate is an …

Objective Our chief objective was to assess whether longer duration of 5α-RI exposure
increases risk of PED, independent of age and other known risk factors. Men with shorter 5α …

Androgens are steroid hormones with pleotropic and diverse biochemical and physiological
functions, and androgen deficiency exerts a negative impact on human health. Testosterone …

Background Dutasteride has been successfully used in treatment of lower urinary tract
symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). However, dutasteride …

Abstract 5α-dihydrotestosterone (5α-DHT) is the most potent natural androgen. 5α-DHT
elicits a multitude of physiological actions, in a host of tissues, including prostate, seminal …