Surveillance of antimicrobial resistance in low-and middle-income countries: a scattered picture

K Iskandar, L Molinier, S Hallit, M Sartelli… - … Resistance & Infection …, 2021 - Springer
Data on comprehensive population-based surveillance of antimicrobial resistance is lacking.
In low-and middle-income countries, the challenges are high due to weak laboratory …

Accelerating antibiotic discovery through artificial intelligence

MCR Melo, JRMA Maasch… - Communications …, 2021 - nature.com
By targeting invasive organisms, antibiotics insert themselves into the ancient struggle of the
host-pathogen evolutionary arms race. As pathogens evolve tactics for evading antibiotics …

ResFinder–an open online resource for identification of antimicrobial resistance genes in next-generation sequencing data and prediction of phenotypes from …

AF Florensa, RS Kaas, PTLC Clausen… - Microbial …, 2022 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …

The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

JJ Davis, AR Wattam, RK Aziz, T Brettin… - Nucleic acids …, 2020 - academic.oup.com
Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …

Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …

Genome-based prediction of bacterial antibiotic resistance

M Su, SW Satola, TD Read - Journal of clinical microbiology, 2019 - Am Soc Microbiol
Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …

Machine learning for antimicrobial resistance prediction: current practice, limitations, and clinical perspective

JI Kim, F Maguire, KK Tsang, T Gouliouris… - Clinical microbiology …, 2022 - Am Soc Microbiol
Antimicrobial resistance (AMR) is a global health crisis that poses a great threat to modern
medicine. Effective prevention strategies are urgently required to slow the emergence and …

Standardized bacteriophage purification for personalized phage therapy

T Luong, AC Salabarria, RA Edwards, DR Roach - Nature protocols, 2020 - nature.com
The world is on the cusp of a post-antibiotic era, but researchers and medical doctors have
found a way forward—by looking back at how infections were treated before the advent of …

Correlation between Phenotypic and In Silico Detection of Antimicrobial Resistance in Salmonella enterica in Canada Using Staramr

A Bharat, A Petkau, BP Avery, JC Chen, JP Folster… - Microorganisms, 2022 - mdpi.com
Whole genome sequencing (WGS) of Salmonella supports both molecular typing and
detection of antimicrobial resistance (AMR). Here, we evaluated the correlation between …

Molecular architecture of early dissemination and massive second wave of the SARS-CoV-2 virus in a major metropolitan area

SW Long, RJ Olsen, PA Christensen, DW Bernard… - MBio, 2020 - Am Soc Microbiol
We sequenced the genomes of 5,085 severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strains causing two coronavirus disease 2019 (COVID-19) disease waves in …