Glioblastoma multiforme (GBM) is the most aggressive type of primary brain tumor and is
associated with a poor clinical prognosis. Despite the progress in the understanding of the …

Glioblastoma is the most aggressive malignant tumor of the central nervous system with a
low survival rate. The difficulty of obtaining this tumor material represents a major limitation …

Abstract Purpose of Review Immunohistochemistry is an integral technique for tissue-based
diagnostics and biomarker detection with broad worldwide adoption. Advances in core …

Glioblastoma is a malignant tumor of the brain. The treatment of this tumor is still a
challenge. Curcumin has been shown to have therapeutic effects when used to treat …

The possible application of BRAF-targeted therapy in brain tumors is growing continuously.
We have analyzed clinical strategies that address BRAF activation in primary brain tumors …

Pilocytic astrocytoma is a central nervous system tumor of slow growth, which represents 5%
of all gliomas and most often develops in the cerebellum (42–60%), but can also arise in …

Background Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic glioma, characterized
by large pleomorphic and frequently multinucleated cells, spindle and lipidized cells, a …

Analyzing the mutational load of driver mutations in melanoma could provide valuable
information regarding its progression. We aimed at analyzing the heterogeneity of …

Aims Pleomorphic xanthoastrocytoma (PXA) is a rare circumscribed glioma, characterized
by frequent BRAF p. V600E mutation, and classified as grade 2 or 3. Owing to overlapping …

Epithelioid glioblastoma is a new variant of glioblastoma that has been recently recognized
in the 2016 WHO classification of brain tumors. Given the rarity of epithelioid glioblastoma …