Review of eukaryote cellular membrane lipid Composition, with special attention to the fatty acids

O Ali, A Szabó - International Journal of Molecular Sciences, 2023 - mdpi.com
Biological membranes, primarily composed of lipids, envelop each living cell. The intricate
composition and organization of membrane lipids, including the variety of fatty acids they …

Cancer immunometabolism: advent, challenges, and perspective

Q Dang, B Li, B Jin, Z Ye, X Lou, T Wang, Y Wang… - Molecular Cancer, 2024 - Springer
For decades, great strides have been made in the field of immunometabolism. A plethora of
evidence ranging from basic mechanisms to clinical transformation has gradually embarked …

Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5

Y Lai, Y Gao, J Lin, F Liu, L Yang, J Zhou, Y Xue, Y Li… - Cell Metabolism, 2024 - cell.com
Immunomodulatory effects of long-chain fatty acids (LCFAs) and their activating enzyme,
acyl-coenzyme A (CoA) synthetase long-chain family (ACSL), in the tumor microenvironment …

Spaceflight alters host-gut microbiota interactions

E Gonzalez, MD Lee, BT Tierney, N Lipieta… - npj Biofilms and …, 2024 - nature.com
The ISS rodent habitat has provided crucial insights into the impact of spaceflight on
mammals, inducing symptoms characteristic of liver disease, insulin resistance, osteopenia …

Evolutionarily related host and microbial pathways regulate fat desaturation in C. elegans

BW Fox, MJ Helf, RN Burkhardt, AB Artyukhin… - Nature …, 2024 - nature.com
Fatty acid desaturation is central to metazoan lipid metabolism and provides building blocks
of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions …

[HTML][HTML] IL-17B alleviates the pathogenesis of systemic lupus erythematosus by inhibiting FASN-mediated differentiation of B cells

Y Xiao, Y Hu, Y Gao, L Wang, L Zhang, Q Ma… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
The interleukin 17 (IL-17) family of cytokines has emerged as a critical player in autoimmune
disease, including systemic lupus erythematosus (SLE). However, the role of IL-17B, a …

Identification of fatty acids synthesis and metabolism-related gene signature and prediction of prognostic model in hepatocellular carcinoma

A Zhengdong, X Xiaoying, F Shuhui, L Rui… - Cancer Cell …, 2024 - Springer
Background Fatty acids synthesis and metabolism (FASM)-driven lipid mobilization is
essential for energy production during nutrient shortages. However, the molecular …

Scd-1 deficiency promotes the differentiation of CD8+ T effector

Y Lin, X Li, H Shan, J Gao, Y Yang, L Jiang… - Frontiers in Cellular …, 2024 - frontiersin.org
The impact of various fatty acid types on adaptive immunity remains uncertain, and their
roles remain unelucidated. Stearoyl-CoA desaturase (Scd) is a Δ-9 desaturase, which is a …

Stearoyl-CoA desaturase-1: a potential therapeutic target for neurological disorders

M Loix, S Vanherle, M Turri, S Kemp… - Molecular …, 2024 - Springer
Disturbances in the fatty acid lipidome are increasingly recognized as key drivers in the
progression of various brain disorders. In this review article, we delve into the impact of Δ9 …

Exploring the influence of the selected conjugated fatty acids isomers and cancerous process on the fatty acids profile of spleen

T Lepionka, M Białek, M Czauderna, W Wojtak… - Cancers, 2024 - mdpi.com
Simple Summary The spleen has recently been recognized for its role in lipid metabolism
and potential influence on cancer development and progression. Our study investigates …