Metagenomic sequencing for infectious disease diagnostics is an important tool that holds
promise for use in the clinical laboratory. Challenges for implementation so far include high …

Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

As whole-genome sequencing becomes an established component of the microbiologist's
toolbox, it is imperative that researchers, clinical microbiologists, and public health …

During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic
inflammation it becomes more susceptible to Staphylococcus aureus. To understand this …

The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of airway infection
in cystic fibrosis (CF) patients. P. aeruginosa employs several hierarchically arranged and …

Standardization and quality assurance of microbiome community analysis by high-
throughput DNA sequencing require widely accessible and well-characterized reference …

The evolution and propagation of antibiotic resistance by bacterial pathogens are significant
threats to global public health. Contemporary DNA sequencing tools were applied here to …

Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic
resistance gene that impact therapeutic options are increasingly observed. Amplification can …

The transcriptomes of Pseudomonas aeruginosa clone C isolates NN2 and SG17M during
the mid-exponential and early stationary phases of planktonic growth were evaluated by …

Carbapenem resistance in Enterobacterales is a public health threat. Klebsiella
pneumoniae carbapenemase (encoded by alleles of the bla KPC family) is one of the most …