It has been proposed that a chronic state of inflammation correlated with aging known as
inflammaging, is implicated in multiple disease states commonly observed in the elderly …

Impaired protein homeostasis and accumulation of damaged or abnormally modified protein
are common disease mechanisms in many neurodegenerative disorders, including …

Melanin is ubiquitous in living organisms across different biological kingdoms of life, making
it an important, natural biomaterial. Its presence in nature from microorganisms to higher …

Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …

Dopamine metabolism, alpha-synuclein pathology, and iron homeostasis have all been
implicated as potential contributors to the unique vulnerability of substantia nigra …

The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …

Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

During Parkinson's disease (PD), both the central nervous system (CNS) and peripheral
nervous system (PNS) are affected. In parallel, innate immune cells respond early to …

Parkinson's disease (PD) is an aging-related disease and the second most common
neurodegenerative disease after Alzheimer's disease. The main symptoms of PD are …

Lanthanide metal-organic frameworks (Ln-MOFs), which is composed of organic bridging
ligands and Ln 3+ ions/clusters, is an important component of luminescent MOFs. Compared …