Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

Posttraumatic stress disorder (PTSD) is characterized by a persistent maladaptive reaction
after exposure to severe psychological trauma. Traumatic events that may precipitate PTSD …

We conducted genome-wide association analyses of over 250,000 participants of European
(EUR) and African (AFR) ancestry from the Million Veteran Program using electronic health …

Background Public Safety Personnel (eg, firefighters, paramedics, and police officers) are
routinely exposed to human suffering and need to make quick, morally challenging …

Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …

Stress and pain are interleaved at multiple levels-interacting and influencing each other.
Both are modulated by psychosocial factors including fears, beliefs, and goals, and are …

Animal models of threat processing have evolved beyond the amygdala to incorporate a
distributed neural network. In human research, evidence has intensified in recent years to …

Responding to different dynamic levels of stress is critical for mammalian survival. Disruption
of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) signaling is proposed to …

Threat and extinction memories are crucial for organisms' survival in changing
environments. These memories are believed to be encoded by separate ensembles of …

Psychosocial stress is a common risk factor for anxiety disorders. The cellular mechanism for
the anxiogenic effect of psychosocial stress is largely unclear. Here, we show that chronic …