[HTML][HTML] Mechanisms regulating intestinal barrier integrity and its pathological implications

C Chelakkot, J Ghim, SH Ryu - Experimental & molecular medicine, 2018 - nature.com
The gastrointestinal tract is a specialized organ in which dynamic interactions between host
cells and the complex environment occur in addition to food digestion. Together with the …

Current and emerging therapeutic targets for IBD

MF Neurath - Nature Reviews Gastroenterology & Hepatology, 2017 - nature.com
Various therapeutic advances have led to a paradigm shift in the clinical management of
patients with IBD. The introduction of immunosuppressive (such as azathioprine) and …

Microbiota dysbiosis and barrier dysfunction in inflammatory bowel disease and colorectal cancers: exploring a common ground hypothesis

LCH Yu - Journal of biomedical science, 2018 - Springer
Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the
interaction of genetic, environmental, barrier and microbial factors leading to chronic …

Chemistry, bioavailability, bioactivity, nutritional aspects and human health benefits of polyphenols: A comprehensive review

MT El-Saadony, T Yang, AM Saad, SS Alkafaas… - International journal of …, 2024 - Elsevier
Polyphenols, including phenolics, alkaloids, and terpenes, are secondary metabolites that
are commonly found in fruits, vegetables, and beverages, such as tea, coffee, wine …

Anti-inflammatory action of green tea

T Ohishi, S Goto, P Monira, M Isemura… - Anti-Inflammatory & …, 2016 - ingentaconnect.com
Background: Green tea has been shown to have beneficial effects against a variety of
diseases such as cancer, obesity, diabetes, cardiovascular disease, and neurodegenerative …

The dual role of neutrophils in inflammatory bowel diseases

O Wéra, P Lancellotti, C Oury - Journal of clinical medicine, 2016 - mdpi.com
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
characterised by aberrant immunological responses leading to chronic inflammation without …

Nonantimicrobial actions of macrolides: overview and perspectives for future development

JA Kricker, CP Page, FR Gardarsson… - Pharmacological …, 2021 - Elsevier
Macrolides are among the most widely prescribed broad spectrum antibacterials, particularly
for respiratory infections. It is now recognized that these drugs, in particular azithromycin …

High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production

PM Miranda, G De Palma, V Serkis, J Lu… - Microbiome, 2018 - Springer
Background Changes in hygiene and dietary habits, including increased consumption of
foods high in fat, simple sugars, and salt that are known to impact the composition and …

Understanding the multifaceted role of neutrophils in cancer and autoimmune diseases

X Wang, L Qiu, Z Li, XY Wang, H Yi - Frontiers in immunology, 2018 - frontiersin.org
Neutrophils are one of the first immune cell types that are recruited to injury and infection
site. As a vital component of the immune system, neutrophils are heterogeneous immune …

[HTML][HTML] Matrix metalloproteinases as regulators of inflammatory processes

B Fingleton - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2017 - Elsevier
Inflammation is a central mechanism for dealing with insults to tissue, either from pathogenic
invaders or by other damage-inducing means, such that the threat is removed, the tissue is …