Thyroid hormones as molecular determinants of thermogenesis

E Silvestri, L Schiavo, A Lombardi… - Acta Physiologica …, 2005 - Wiley Online Library
Thyroid hormones (TH) are major modulators of energy metabolism and thermogenesis. It is
generally believed that 3, 5, 3′‐triiodo‐l‐thyronine (T3) is the only active form of TH, and …

Thyroid hormones and the mechanisms of adaptation to cold

S Tsibulnikov, L Maslov, N Voronkov, P Oeltgen - Hormones, 2020 - Springer
The thyroid gland plays a crucial role in the regulation of metabolism, oxygen consumption,
and the release of energy in the form of heat to maintain the body. Even at rest, these …

Seasonal acclimatization of metabolism in Eurasian tree sparrows (Passer montanus)

WH Zheng, M Li, JS Liu, SL Shao - … and Physiology Part A: Molecular & …, 2008 - Elsevier
Acclimatization to winter conditions is an essential prerequisite for survival of small
passerines of the northern temperate zone. Changes in photoperiod, ambient temperature …

Chronic cold exposure induces mitochondrial plasticity in deer mice native to high altitudes

S Mahalingam, ZA Cheviron, JF Storz… - The Journal of …, 2020 - Wiley Online Library
Key points Small mammals native to high altitude must sustain high rates of thermogenesis
to cope with cold. Skeletal muscle is a key site of shivering and non‐shivering …

Increased fatigue resistance linked to Ca2+‐stimulated mitochondrial biogenesis in muscle fibres of cold‐acclimated mice

JD Bruton, J Aydin, T Yamada… - The Journal of …, 2010 - Wiley Online Library
Mammals exposed to a cold environment initially generate heat by repetitive muscle activity
(shivering). Shivering is successively replaced by the recruitment of uncoupling protein‐1 …

The role of the sympathetic nervous system and uncoupling proteins in the thermogenesis induced by 3, 4-methylenedioxymethamphetamine

EM Mills, DE Rusyniak, JE Sprague - Journal of molecular medicine, 2004 - Springer
Body temperature regulation involves a homeostatic balance between heat production and
dissipation. Sympathetic agents such as 3, 4-methylenedioxymethamphetamine (MDMA …

Cold adaptation and thyroid hormone metabolism

P Laurberg, S Andersen… - Hormone and Metabolic …, 2005 - thieme-connect.com
Resting oxygen consumption and energy expenditure is sensitive to slight alterations in
thyroid function. This means that timing and magnitude of cold adaptation would to some …

[HTML][HTML] Effects of mild chronic intermittent cold exposure on rat organs

X Wang, H Che, W Zhang, J Wang, T Ke… - … Journal of Biological …, 2015 - ncbi.nlm.nih.gov
Cold adaptation is a body's protective response to cold stress. Mild chronic intermittent cold
(CIC) exposure has been used to generate animal models for cold adaptation studies …

Regulation of thermogenesis by the central melanocortin system

W Fan, A Voss-Andreae, WH Cao, SF Morrison - Peptides, 2005 - Elsevier
Adaptive thermogenesis represents one of the important homeostatic mechanisms by which
the body maintains appropriate levels of stored energy and its core temperature …

Cold Tolerance in Hypothyroid Rabbits: Role of Skeletal Muscle Mitochondria and Sarcoplasmic Reticulum Ca2+ ATPase Isoform 1 Heat Production

AP Arruda, LA Ketzer, M Nigro, A Galina… - …, 2008 - academic.oup.com
Brown adipose tissue (BAT) is involved in rat and mice thermoregulation, and heat produced
by BAT depends on the concerted action of thyroid hormones and catecholamines. Little is …