Abstract Purpose of Review The infant gut microbiota has become a focus of multiple
epidemiologic and cohort studies. This microbiome is derived from the mother (via the …

Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …

Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

Methods This paper arose from an extensive literature review undertaken in developing the
Canadian Healthy Infant Longitudinal Development (CHILD) study, a multicentre national …

Objective To examine the associations between pet keeping in early childhood and asthma
and allergies in children aged 6–10 years. Design Pooled analysis of individual participant …

Allergen exposure is associated with the development of allergen‐specific sensitization, but
their relationship is influenced by other contemporaneous exposures (such as microbial …

Importance The association between early exposure to animals and childhood asthma is not
clear, and previous studies have yielded contradictory results. Objective To determine …

Asthma has become the most common, childhood chronic disease in the industrialized
world, and it is also increasing in developing regions. There are huge differences in the …

Background Studies examining associations of early-life cat and dog ownership with
childhood asthma have reported inconsistent results. Several factors could explain these …

Background: Exposure to pets has been implicated as a risk factor for asthma. However, this
relation has been difficult to assess in individual studies because of the large potential of …