Raman spectroscopy: techniques and applications in the life sciences

DW Shipp, F Sinjab, I Notingher - Advances in Optics and Photonics, 2017 - opg.optica.org
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Methods and applications of Raman microspectroscopy to single-cell analysis

IW Schie, T Huser - Applied spectroscopy, 2013 - journals.sagepub.com
Raman spectroscopy is a powerful biochemical analysis technique that allows for the
dynamic characterization and imaging of living biological cells in the absence of fluorescent …

Artificial intelligent label-free SERS profiling of serum exosomes for breast cancer diagnosis and postoperative assessment

Y Xie, X Su, Y Wen, C Zheng, M Li - Nano letters, 2022 - ACS Publications
Breast cancer subtypes have important implications of treatment responses and clinical
outcomes. Exosomes have been considered as promising biomarkers for liquid biopsies, but …

Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy

Y Zhou, CH Liu, B Wu, X Yu, G Cheng… - … of biomedical optics, 2019 - spiedigitallibrary.org
Glioma is one of the most refractory types of brain tumor. Accurate tumor boundary
identification and complete resection of the tumor are essential for glioma removal during …

Label-free plasmon-enhanced spectroscopic HER2 detection for dynamic therapeutic surveillance of breast cancer

Y Xie, Y Wen, X Su, C Zheng, M Li - Analytical Chemistry, 2022 - ACS Publications
The expression of human epidermal growth factor receptor-2 (HER2) has important
implications for pathogenesis, progression, and therapeutic efficacy of breast cancer. The …

The lipid-reactive oxygen species phenotype of breast cancer. Raman spectroscopy and mapping, PCA and PLSDA for invasive ductal carcinoma and invasive …

J Surmacki, B Brozek-Pluska, R Kordek, H Abramczyk - Analyst, 2015 - pubs.rsc.org
Vibrational signatures of human breast tissue (invasive ductal carcinoma and invasive
lobular carcinoma) were used to identify, characterize and discriminate structures in normal …

Mechanical trap surface‐enhanced Raman spectroscopy for three‐dimensional surface molecular imaging of single live cells

Q Jin, M Li, B Polat, SK Paidi, A Dai… - Angewandte …, 2017 - Wiley Online Library
Reported is a new shell‐based spectroscopic platform, named mechanical trap surface‐
enhanced Raman spectroscopy (MTSERS), for simultaneous capture, profiling, and 3D …

A reliable Raman-spectroscopy-based approach for diagnosis, classification and follow-up of B-cell acute lymphoblastic leukemia

S Managò, C Valente, P Mirabelli, D Circolo, F Basile… - Scientific reports, 2016 - nature.com
Acute lymphoblastic leukemia type B (B-ALL) is a neoplastic disorder that shows high
mortality rates due to immature lymphocyte B-cell proliferation. B-ALL diagnosis requires …

[HTML][HTML] The biochemical, nanomechanical and chemometric signatures of brain cancer

H Abramczyk, A Imiela - Spectrochimica Acta Part A: Molecular and …, 2018 - Elsevier
Raman spectroscopy and imaging combined with AFM topography and mechanical
indentation by AFM have been shown to be an effective tool for analysis and discrimination …

Raman spectroscopy and convolutional neural networks for monitoring biochemical radiation response in breast tumour xenografts

AM Fuentes, A Narayan, K Milligan, JJ Lum… - Scientific Reports, 2023 - nature.com
Tumour cells exhibit altered metabolic pathways that lead to radiation resistance and
disease progression. Raman spectroscopy (RS) is a label-free optical modality that can …