[HTML][HTML] MicroRNA-98: the multifaceted regulator in human cancer progression and therapy

V Hazari, SA Samali, P Izadpanahi… - Cancer Cell …, 2024 - ncbi.nlm.nih.gov
Abstract MicroRNA-98 (miR-98) stands as an important molecule in the intricate landscape
of oncology. As a subset of microRNAs, these small non-coding RNAs have accompanied a …

Expression levels and clinical values of miR-92b-3p in breast cancer

Y Du, Z Miao, K Wang, Y Lv, L Qiu, L Guo - World Journal of Surgical …, 2021 - Springer
Background miR-92b is a carcinogenic miRNA that has great potential as a biomarker for
disease prognosis, diagnosis, and treatment in the clinic. It is of great significance to analyse …

MicroRNA-92a-3p enhances functional recovery and suppresses apoptosis after spinal cord injury via targeting phosphatase and tensin homolog

S He, Z Wang, Y Li, J Dong, D Xiang, L Ren… - Bioscience …, 2020 - portlandpress.com
Spinal cord injury (SCI) is a neurological disease commonly caused by traumatic events on
spinal cords. MiRNA-92a-3p is reported to be down-regulated after SCI. Our study …

Predictive efficacy of MiR-125b-5p, MiR-17-5p, and MiR-185-5p in liver metastasis and chemotherapy response among advanced stage colorectal cancer patients

D Sur, L Balacescu, SS Cainap, S Visan, L Pop… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs), a class of small non-coding RNAs represent potential biomarkers for
colorectal cancer (CRC). The study hypothesized that miRNAs associated with liver …

miRNAs‐Based Molecular Signature for KRAS Mutated and Wild Type Colorectal Cancer: An Explorative Study

E Milanesi, M Dobre, AI Bucuroiu… - Journal of …, 2020 - Wiley Online Library
microRNAs (miRNAs) have been proposed as promising molecular biomarkers for
diagnosis, prognosis, and responsive therapeutic targets in different types of cancer …

A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer

E Høye, B Fromm, PHM Böttger, D Domanska… - NAR …, 2022 - academic.oup.com
Although microRNAs (miRNAs) contribute to all hallmarks of cancer, miRNA dysregulation in
metastasis remains poorly understood. The aim of this work was to reliably identify miRNAs …

Development of a miRNA‐based classifier for detection of colorectal cancer molecular subtypes

RS Adam, D Poel, L Ferreira Moreno… - Molecular …, 2022 - Wiley Online Library
Previously, colorectal cancer (CRC) has been classified into four distinct molecular subtypes
based on transcriptome data. These consensus molecular subtypes (CMSs) have …

Adaptive group-regularized logistic elastic net regression

MM Münch, CFW Peeters, AW Van Der Vaart… - …, 2021 - academic.oup.com
In high-dimensional data settings, additional information on the features is often available.
Examples of such external information in omics research are:(i)-values from a previous study …

Identification of a potentially functional microRNA–mRNA regulatory network in lung adenocarcinoma using a Bioinformatics analysis

XJ Wang, J Gao, Z Wang, Q Yu - Frontiers in cell and developmental …, 2021 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a common lung cancer with a high mortality,
for which microRNAs (miRNAs) play a vital role in its regulation. Multiple messenger RNAs …

miR-92b-3p Regulates Cell Cycle and Apoptosis by Targeting CDKN1C, Thereby Affecting the Sensitivity of Colorectal Cancer Cells to Chemotherapeutic Drugs

F Zhao, Z Yang, X Gu, L Feng, M Xu, X Zhang - Cancers, 2021 - mdpi.com
Simple Summary Multidrug resistance (MDR) limits the effectiveness of colorectal cancer
(CRC) treatment and miRNAs play an important role in drug resistance. To search for …